NADA
- ₹0
- Product name: NADA
- CAS: 199875-69-9
- MF: C28H41NO3
- MW: 439.63
- EINECS:
- MDL Number:MFCD03412031
- Synonyms:ARACHIDONOYLDOPAMIDE;ARACHIDONOYL DOPAMINE;AA-DA;NADA;N-ARACHIDONOYL-3-HYDROXYTYRAMINE;N-ARACHIDONOYLDOPAMINE;N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;N-(3,4-Dihydroxyphenethyl)acetamide
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Properties
Boiling point :640.0±55.0 °C(Predicted)
Density :1.023±0.06 g/cm3(Predicted)
Flash point :14 °C
storage temp. :−20°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :9.79±0.10(Predicted)
form :ethanol solution
color :Pale yellow
Sensitive :Air Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Subject to air oxidation Solutions in DMSO may be stored at -80° under an inert atmosphere for up to 1 month.
Density :1.023±0.06 g/cm3(Predicted)
Flash point :14 °C
storage temp. :−20°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :9.79±0.10(Predicted)
form :ethanol solution
color :Pale yellow
Sensitive :Air Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Subject to air oxidation Solutions in DMSO may be stored at -80° under an inert atmosphere for up to 1 month.
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||||||||||
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Description
Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA), have been isolated and characterized from bovine brain. NADA is the amide of the neurotransmitter dopamine and arachidonic acid. NADA is a CB1-selective agonist, inducing the typical tetrad of hypothermia, analgesia, catalepsy, and hypomotility in rats which exceeds that of anandamide (AEA). NADA is a full agonist at the vanilloid receptor 1, but is inactive on the dopaminergic D1 and D2 receptors. NADA is also a potent inhibitor (IC50 = 0.25 μM) of the proliferation of MCF-7 breast carcinoma cells. Recent reports of NADA’s endothelium-dependent vasodilation indicate that some of its cannabinergic activities antagonized by SR141716A may be non-CB1/CB2 dependent.More related product prices
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Suppliers and manufacturers
Nantong HI-FUTURE Biology Co., Ltd.
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
Changsha Fuzhen Biotechnology Co.,LTD
InvivoChem
SHANGHAI ZZBIO CO., LTD.
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Nantong Hi-Future Biotechnology Co., Ltd
Elucigen bio
Beijing Stronger Science Co., Ltd.