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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >Nigericin sodium salt

Nigericin sodium salt

Nigericin sodium salt Structure
  • ₹6990 - ₹82118.45
  • Product name: Nigericin sodium salt
  • CAS: 28643-80-3
  • MF: C40H69NaO11
  • MW: 748.97
  • EINECS:608-231-4
  • MDL Number:MFCD30377206
  • Synonyms:Polyetherin A, Azalomycin M, Helixin C, Antibiotic K178, Antibiotic X-464;Antibiotic K178, Antibiotic X464, Azalomycin M, Helexin C, Polyetherin A;Sodium (2R)-2-[(3S,6R)-6-[[(2S,4R,5R,7R,9R,10R)-2-[(5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl]-3-methyloxan-2-yl]propanoate;Nigericin, monosodium salt;Nsc292567;Nigericin sodium salt,Antibiotic K178, Antibiotic X464, Azalomycin M, Helexin C, Polyetherin A;Nigericin sodiuM sa;Polyetherin A, AzaloMycin M, Helixin C, K 178, X 464, Pandavir
6 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 50MG
  • 1ML
  • ManufacturerSigma-Aldrich(India)
  • Product number481990
  • Product descriptionNigericin, Sodium Salt, Streptomyces hygroscopicus - CAS 28643-80-3 - Calbiochem Disrupts the membrane potential and stimulates ATPase activity in mitochondria.
  • Packaging5MG
  • Price₹6990
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1779
  • Product descriptionNigericin sodium salt Ready Made Solution 5?mg/mL (DMSO:ethanol 1:1)
  • Packaging1ML
  • Price₹12674.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7143
  • Product descriptionNigericin sodium salt ≥98% (TLC)
  • Packaging5MG
  • Price₹12784.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number481990
  • Product descriptionNigericin, Sodium Salt, Streptomyces hygroscopicus - CAS 28643-80-3 - Calbiochem Disrupts the membrane potential and stimulates ATPase activity in mitochondria.
  • Packaging10MG
  • Price₹15280
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7143
  • Product descriptionNigericin sodium salt ≥98% (TLC)
  • Packaging10MG
  • Price₹21455.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7143
  • Product descriptionNigericin sodium salt ≥98% (TLC)
  • Packaging50MG
  • Price₹82118.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 481990 Nigericin, Sodium Salt, Streptomyces hygroscopicus - CAS 28643-80-3 - Calbiochem Disrupts the membrane potential and stimulates ATPase activity in mitochondria. 5MG ₹6990 2022-06-14 Buy
Sigma-Aldrich(India) SML1779 Nigericin sodium salt Ready Made Solution 5?mg/mL (DMSO:ethanol 1:1) 1ML ₹12674.9 2022-06-14 Buy
Sigma-Aldrich(India) N7143 Nigericin sodium salt ≥98% (TLC) 5MG ₹12784.33 2022-06-14 Buy
Sigma-Aldrich(India) 481990 Nigericin, Sodium Salt, Streptomyces hygroscopicus - CAS 28643-80-3 - Calbiochem Disrupts the membrane potential and stimulates ATPase activity in mitochondria. 10MG ₹15280 2022-06-14 Buy
Sigma-Aldrich(India) N7143 Nigericin sodium salt ≥98% (TLC) 10MG ₹21455.15 2022-06-14 Buy
Sigma-Aldrich(India) N7143 Nigericin sodium salt ≥98% (TLC) 50MG ₹82118.45 2022-06-14 Buy

Properties

Melting point :approximate 255℃
storage temp. :2-8°C
solubility :Soluble in chloroform, methanol or ethanol
form :solution
color :White
Merck :13,6569
BRN :3892398
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :MOYOTUKECQMGHE-NTQCAYBPSA-M
LogP :4.817 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Nigericin is an antibiotic derived from S. hygroscopicus that acts as a potassium ionophore promoting K+/H+ exchange across mitochondrial membranes. Nigericin can be used as a research tool to disrupt intracellular H+ and K+ concentration, thus altering pH, membrane potential, and cell volume. At 10 μM, nigericin induces egress of T. gondii parasites by inducing efflux of K+.

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