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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Olmesartan Medoxomil

Olmesartan Medoxomil

Olmesartan Medoxomil Structure
  • ₹6100 - ₹45410.88
  • Product name: Olmesartan Medoxomil
  • CAS: 144689-63-4
  • MF: C29H30N6O6
  • MW: 558.59
  • EINECS:604-433-1
  • MDL Number:MFCD00944911
  • Synonyms:(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl] 4-yl)methyl)-4-(;OlMesartan MedoxoMil SynoyM:4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-iMidazole-5-carboxylic acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl ester;OLMESARTAN MEDOXOMIL USP ORGANIC CHEMICA;OMST;1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester;Olmesartan medoxomil for system suitability;Olmesartan MedoxomiI;Olmesartan Medoxomi
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 200MG
  • 250MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberO0510
  • Product descriptionOlmesartan Medoxomil
  • Packaging1G
  • Price₹6100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberO0510
  • Product descriptionOlmesartan Medoxomil
  • Packaging5G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1391
  • Product descriptionOlmesartan medoxomil ≥98% (HPLC)
  • Packaging50MG
  • Price₹11539.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1851
  • Product descriptionOlmesartan Medoxomil Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging200MG
  • Price₹22743.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1391
  • Product descriptionOlmesartan medoxomil ≥98% (HPLC)
  • Packaging250MG
  • Price₹45410.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) O0510 Olmesartan Medoxomil 1G ₹6100 2022-05-26 Buy
TCI Chemicals (India) O0510 Olmesartan Medoxomil 5G ₹9800 2022-05-26 Buy
Sigma-Aldrich(India) SML1391 Olmesartan medoxomil ≥98% (HPLC) 50MG ₹11539.45 2022-06-14 Buy
Sigma-Aldrich(India) PHR1851 Olmesartan Medoxomil Pharmaceutical Secondary Standard; Certified Reference Material 200MG ₹22743.33 2022-06-14 Buy
Sigma-Aldrich(India) SML1391 Olmesartan medoxomil ≥98% (HPLC) 250MG ₹45410.88 2022-06-14 Buy

Properties

Melting point :180°C
Boiling point :804.2±75.0 °C(Predicted)
Density :1.38±0.1 g/cm3(Predicted)
Flash point :180°C
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :4.15±0.10(Predicted)
form :powder
color :white to beige
Decomposition :180 ºC
InChIKey :UQGKUQLKSCSZGY-UHFFFAOYSA-N
SMILES :C1(CCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C(C(OCC2=C(C)OC(=O)O2)=O)=C(C(O)(C)C)N=1
CAS DataBase Reference :144689-63-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Olmesartan Medoxomil is a synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland, thereby competing angiotensin II binding to the receptor. This prevents angiotensin II-induced vasoconstriction and decreases aldosterone production, thereby preventing aldosterone-stimulated sodium retention and potassium excretion.

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