EPROSARTAN
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- ₹0
- Product name: EPROSARTAN
- CAS: 133040-01-4
- MF: C23H24N2O4S
- MW: 424.51
- EINECS:
- MDL Number:MFCD00897872
- Synonyms:4-[2-Butyl-5-(2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-benzoic acid;EPROSARTAN;Eprosartan Mysylate;(E)-3-[2-Butyl-1-[(4-carboxyphenyl)-methyl]imidazol-5-l]-2-(2-thienylmethyl)-2-propenoic Acid;((E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoic Acid;SKF-108566);SKF-108566J;Teveten
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Properties
Melting point :250-253°C
storage temp. :Sealed in dry,2-8°C
solubility :Dichloromethane (Slightly), Methanol (Slightly)
form :Solid
color :Pale Yellow to Light Yellow
CAS DataBase Reference :133040-01-4
storage temp. :Sealed in dry,2-8°C
solubility :Dichloromethane (Slightly), Methanol (Slightly)
form :Solid
color :Pale Yellow to Light Yellow
CAS DataBase Reference :133040-01-4
Safety Information
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Description
Teveten was launched in Germany for the treatment of hypertension. There are several ways in which it has been prepared, the shortest of which is four steps; beginning with displacement of 2-butyl-4-chloroimidazole-5-carboxaldehyde with methyl 4-(bromomethyl)benzoate. Teveten is an angiotensin Ⅱ antagonist selective for the AT, subtype receptor. It is a potent, highly selective, competitve antagonist with no agonist activity. Duration of action is similar to Enalapril (greater than 12 hr) but Teveten had a faster onset. While it is orally active, it rapidly dissociates from the receptor. This is contrary to its prolonged duration of action, which presumably results from slow removal from compartments within tissue, cells or matrix around the AT, receptor. It is not bound by BSA.More related product prices
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