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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >Oxolinic acid

Oxolinic acid

Oxolinic acid Structure
  • ₹5910.45 - ₹44404.15
  • Product name: Oxolinic acid
  • CAS: 14698-29-4
  • MF: C13H11NO5
  • MW: 261.23
  • EINECS:238-750-8
  • MDL Number:MFCD00056775
  • Synonyms:1-ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylicacid ;1-ethyl-6,7-methylenedioxo-4-quinoline-3-carboxlicacid ;utibid ;w4565 ;OXOLINIC ACID;5,8-DIHYDRO-5-ETHYL-8-OXO-1,3-DIOXOLO[4,5-G]QUINOLINE-7-CARBOXYLIC ACID;5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid;AKOS 94417
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • SRL

Package

  • 100MG
  • 5G
  • 25G
  • 5Gms
  • 25Gms
  • ManufacturerSigma-Aldrich(India)
  • Product number67126
  • Product descriptionOxolinic acid analytical standard
  • Packaging100MG
  • Price₹5910.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO0877
  • Product descriptionOxolinic acid quinolone antibiotic
  • Packaging5G
  • Price₹11712.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO0877
  • Product descriptionOxolinic acid quinolone antibiotic
  • Packaging25G
  • Price₹44404.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number91088
  • Product descriptionOxolinic Acid (OXO), 99%
  • Packaging5Gms
  • Price₹8770
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number91088
  • Product descriptionOxolinic Acid (OXO), 99%
  • Packaging25Gms
  • Price₹32890
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 67126 Oxolinic acid analytical standard 100MG ₹5910.45 2022-06-14 Buy
Sigma-Aldrich(India) O0877 Oxolinic acid quinolone antibiotic 5G ₹11712.65 2022-06-14 Buy
Sigma-Aldrich(India) O0877 Oxolinic acid quinolone antibiotic 25G ₹44404.15 2022-06-14 Buy
SRL 91088 Oxolinic Acid (OXO), 99% 5Gms ₹8770 2022-05-26 Buy
SRL 91088 Oxolinic Acid (OXO), 99% 25Gms ₹32890 2022-05-26 Buy

Properties

Melting point :314-316°C (dec.)
Boiling point :473℃
Density :1.3038 (rough estimate)
refractive index :1.5500 (estimate)
Flash point :>110°(230°F)
storage temp. :2-8°C
solubility :Soluble in 0.5N NaOH with warming
form :Crystalline Powder
pka :5.94±0.20(Predicted)
color :White
Water Solubility :3.214mg/L(temperature not stated)
Sensitive :Light Sensitive
Merck :13,7014
BRN :620635
Stability :Stable. Combustible.
InChIKey :KYGZCKSPAKDVKC-UHFFFAOYSA-N
CAS DataBase Reference :14698-29-4(CAS DataBase Reference)
EPA Substance Registry System :Oxolinic acid (14698-29-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Developed in Japan in the 1970s, oxolinic acid belongs to the family of quinolone antibiotic, which is a synthetic antimicrobial agent aiming at gram-negative bacteria, especially those responsible for urinary tract infections. It is also commonly used in clinical for microbiological antimicrobial susceptibility tests against gram negative microbial isolates, providing antibiotic treatment options for infected patients. It can serve as a selective agent in several types of isolation media, for example, to isolate Gardnerella vaginalis. Besides, oxolinic acid can be applied in agriculture, which has proved to be effective against the seed-borne pathogen, such as Burkholderia glumae, a bacteria inducing grain rot, sheath rot, seedling rot, and bacterial panicle blight.
Oxolinic acid works by targeting DNA gyrase or topoisomerase II, enzymes vital for DNA synthesis, which ultimately inhibits DNA synthesis and cell division.

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Suppliers and manufacturers

CNS CHEMICALS A.J Chemicals CLEARSYNTH LABS LTD. Reax Chemicals Pharmaffiliates Analytics & Synthetics (P) Ltd. Rawia International HealthCare Pvt. Ltd. Pharma Affiliates Cns Chemicals Esschem Pvt., Ltd. HiMedia Laboratories