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P7C3

P7C3 Structure
  • ₹13931.78 - ₹56084.33
  • Product name: P7C3
  • CAS: 301353-96-8
  • MF: C21H18Br2N2O
  • MW: 474.19
  • EINECS:
  • MDL Number:MFCD00572918
  • Synonyms:P7C3;1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(PHENYLAMINO)PROPAN-2-OL;3,6-Dibromo-a-[(phenylamino)methyl]-9H-carbazole-9-ethanol;P7C3, >=98%;6-Dibromo-α-[(phenylamino)methyl]-9H-carbazole-9-ethanol;P7C3; 301353-96-8;CS-1463;P7C3, >97%
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD8446
  • Product descriptionP7C3 ≥98% (HPLC)
  • Packaging5MG
  • Price₹13931.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD8446
  • Product descriptionP7C3 ≥98% (HPLC)
  • Packaging25MG
  • Price₹56084.33
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D8446 P7C3 ≥98% (HPLC) 5MG ₹13931.78 2022-06-14 Buy
Sigma-Aldrich(India) D8446 P7C3 ≥98% (HPLC) 25MG ₹56084.33 2022-06-14 Buy

Properties

Boiling point :656.4±55.0 °C(Predicted)
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble34mg/mL
pka :13.91±0.20(Predicted)
form :powder
color :white to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

P7C3 is an orally bioavailable and brain penetrant aminopropyl carbazole that exhibits proneurogenic and neuroprotective activity by preventing apoptosis of newly postmitotic neurons in the subgranular zone of the hippocampal dentate gyrus. At doses of 5 mg/kg and above, it has been shown to promote the survival of neurons in various rodent models of neurodegeneration or nerve injury. While the precise mechanism of action through which these effects are exerted remains uncertain, P7C3 recently has been shown to bind nicotinamide phosphoribosyltransferase, the rate-limiting enzyme involved in the conversion of nicotinamide into NAD.

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