PF-04620110
- ₹12394.63 - ₹50076.45
- Product name: PF-04620110
- CAS: 1109276-89-2
- MF: C21H24N4O4
- MW: 396.44
- EINECS:
- MDL Number:MFCD19443642
- Synonyms:Cyclohexaneacetic acid, 4-[4-(4-amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-, trans-;2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetic acid;2-(4-(4-(4-aMiNA-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetic acid;2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f]-[1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl);2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetic acid;2-[4-[4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid;2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f]-[1,4]oxazepin-6(5H)-yl)phenyl)cyclohex;PF-04620110
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0207
- Product descriptionPF-04620110 ≥98% (HPLC)
- Packaging5MG
- Price₹12394.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0207
- Product descriptionPF-04620110 ≥98% (HPLC)
- Packaging25MG
- Price₹50076.45
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PZ0207 | PF-04620110 ≥98% (HPLC) | 5MG | ₹12394.63 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PZ0207 | PF-04620110 ≥98% (HPLC) | 25MG | ₹50076.45 | 2022-06-14 | Buy |
Properties
Boiling point :701.9±60.0 °C(Predicted)
Density :1.326
storage temp. :room temp
solubility :DMSO: soluble10mg/mL (clear solution)
pka :4.72±0.10(Predicted)
form :powder
color :white to beige
Density :1.326
storage temp. :room temp
solubility :DMSO: soluble10mg/mL (clear solution)
pka :4.72±0.10(Predicted)
form :powder
color :white to beige
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) catalyzes the final committed step in the biosynthesis of triglycerides and has potential roles in obesity, diabetes, and atherosclerosis. PF-04620110 is a potent inhibitor of DGAT-1 (IC50 = 19 nM) that is without effect on DGAT-2. It has high oral bioavailability (100%) in rats, with a moderate half-life of 6.8 hours. PF-04620110 significantly blocks an increase in plasma triglyceride levels following a corn oil bolus in rats.Related product price
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