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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Stem Cells & Wnt >Wnt / beta-catenin inhibitors >IWP-2

IWP-2

IWP-2 Structure
  • ₹12940 - ₹62481.9
  • Product name: IWP-2
  • CAS: 686770-61-6
  • MF: C22H18N4O2S3
  • MW: 466.6
  • EINECS:
  • MDL Number:MFCD04457599
  • Synonyms:IWP 2;N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide;Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-;IWP 2 N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2d]pyrimidin-2-yl)thio]acetamide;IWP 2, >=98%;IWP-2;IWP 2;Wnt Antagonist II, IWP-2 ;N-(6-methylbenzo[d]thiazol-2-yl)-2-((4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
Price5 Properties Safety Information Description
5 prices
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Brand

  • Sigma-Aldrich
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich
  • Product number681671
  • Product descriptionWnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem The Wnt Antagonist II, IWP-2, also referenced under CAS 686770-61-6, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
  • Packaging10MG
  • Price₹14260
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.06072
  • Product descriptionInSolution Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2) in DMSO.
  • Packaging5MG
  • Price₹12940
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number681671
  • Product descriptionWnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem The Wnt Antagonist II, IWP-2, also referenced under CAS 686770-61-6, controls the biological activity of Wnt. This small molecule/inhibitor is primari
  • Packaging10MG
  • Price₹14260
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI0536
  • Product descriptionIWP-2 ≥98% (HPLC)
  • Packaging5MG
  • Price₹15869.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI0536
  • Product descriptionIWP-2 ≥98% (HPLC)
  • Packaging25MG
  • Price₹62481.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 681671 Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem The Wnt Antagonist II, IWP-2, also referenced under CAS 686770-61-6, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications. 10MG ₹14260 2022-06-14 Buy
Sigma-Aldrich(India) 5.06072 InSolution Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2) in DMSO. 5MG ₹12940 2022-06-14 Buy
Sigma-Aldrich(India) 681671 Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem The Wnt Antagonist II, IWP-2, also referenced under CAS 686770-61-6, controls the biological activity of Wnt. This small molecule/inhibitor is primari 10MG ₹14260 2022-06-14 Buy
Sigma-Aldrich(India) I0536 IWP-2 ≥98% (HPLC) 5MG ₹15869.45 2022-06-14 Buy
Sigma-Aldrich(India) I0536 IWP-2 ≥98% (HPLC) 25MG ₹62481.9 2022-06-14 Buy

Properties

Melting point :257 °C(dec.)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >5mg/mL
pka :9.01±0.70(Predicted)
form :powder
color :Beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey :WRKPZSMRWPJJDH-UHFFFAOYSA-N
CAS DataBase Reference :686770-61-6

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses.

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