PHYSOSTIGMINE
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- ₹0
- Product name: PHYSOSTIGMINE
- CAS: 57-47-6
- MF: C15H21N3O2
- MW: 275.35
- EINECS:200-332-8
- MDL Number:MFCD00151090
- Synonyms:PHYSOSTIGMINE95%,99%;Cogmine;NSC 30782;Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS,8aR)- (9CI);Pyrrolo[2,3-b]indol-5-old,1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-,methylcarbamate(ester),(3aS-cis)-;PHSOSTIGMINE AKA ESERINE;Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester;Methylcarbamic acid (3aS)-1,2,3,3aα,8,8aα-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl ester
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Properties
Melting point :102-104 °C(lit.)
alpha :D17 -76° (c = 1.3 in chloroform); D25 -120° (benzene)
Boiling point :418.29°C (rough estimate)
Density :1.166±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5600 (estimate)
Flash point :>100℃
storage temp. :2-8°C
solubility :Chloroform (Slightly, Sonicated), DMSO (Slightly), Ethanol (Slightly), Methanol
form :Powder
pka :6.12, 12.24(at 25℃)
color :Off-white
Water Solubility :Soluble in water (1:75), alcohol (1:10), chloroform (1:1), ether (1:30), and DMSO.
Sensitive :Air & Light Sensitive
Merck :7384
CAS DataBase Reference :57-47-6(CAS DataBase Reference)
EPA Substance Registry System :Physostigmine (57-47-6)
alpha :D17 -76° (c = 1.3 in chloroform); D25 -120° (benzene)
Boiling point :418.29°C (rough estimate)
Density :1.166±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5600 (estimate)
Flash point :>100℃
storage temp. :2-8°C
solubility :Chloroform (Slightly, Sonicated), DMSO (Slightly), Ethanol (Slightly), Methanol
form :Powder
pka :6.12, 12.24(at 25℃)
color :Off-white
Water Solubility :Soluble in water (1:75), alcohol (1:10), chloroform (1:1), ether (1:30), and DMSO.
Sensitive :Air & Light Sensitive
Merck :7384
CAS DataBase Reference :57-47-6(CAS DataBase Reference)
EPA Substance Registry System :Physostigmine (57-47-6)
Safety Information
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Description
Eserine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor obtained from the Calabar bean, used to treat glaucoma and delayed gastric emptying. This compound has been used as a positive control in a study investigating acetylcholinesterase inhibitors for potential antihelminthic drug targets. Additionally, this parasympathomimetic compound is reported to cross the blood-brain barrier. It is also used as a veterinary medication.Related product price
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Suppliers and manufacturers
Pharma Affiliates
CLEARSYNTH LABS LTD.
Pharmaffiliates Analytics and Synthetics P. Ltd
Neostar United (Changzhou) Industrial Co., Ltd.
TargetMol Chemicals Inc.
Hefei TNJ Chemical Industry Co.,Ltd.
ANHUI WITOP BIOTECH CO., LTD