PI 828
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- ₹15469.99
- Product name: PI 828
- CAS: 942289-87-4
- MF: C19H18N2O3
- MW: 322.36
- EINECS:
- MDL Number:MFCD11100185
- Synonyms:PI 828;2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one;8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one;8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one;LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem;LY 294002, 4′-NH2;PI 828,PI828;4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number440206
- Product descriptionLY 294002, 4ʹ-NH₂ - CAS 942289-87-4 - Calbiochem A cell-permeable LY 294002 4′-amino derivative with enhanced potency against p110α/β/δ/γ.
- Packaging5MG
- Price₹15469.99
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 440206 | LY 294002, 4ʹ-NH₂ - CAS 942289-87-4 - Calbiochem A cell-permeable LY 294002 4′-amino derivative with enhanced potency against p110α/β/δ/γ. | 5MG | ₹15469.99 | 2022-06-14 | Buy |
Properties
Boiling point :534.2±50.0 °C(Predicted)
Density :1.316±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble
pka :4.14±0.10(Predicted)
form :Off-white solid
color :White to yellow
Density :1.316±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble
pka :4.14±0.10(Predicted)
form :Off-white solid
color :White to yellow
Safety Information
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Description
LY 294002, 4′-NH2 is a cell permeable 4′-amino derivative which inhibits the p110α, p110β, p110δ, and p110γ subunits of PI 3-kinase. LY 294002, 4′-NH2 functions by preventing the phosphorylation of Akt1 in the PI 3-kinase/Akt1/mTOR pathway. In addition, the 4′ end of LY 294002, 4′-NH2 can be immobilized on an epoxy containing solid surface, which is beneficial for binding studies. Moreover, studies suggest that LY 294002, 4′-NH2 interacts with non-PI 3-kinase cellular proteins such as mTOR, ALDH1, Brd4, GSK3β and CKIIα. Another useful characteristic of LY 294002, 4′-NH2 is that it functions as a reversible inhibitor of PI 3-kinase.More related product prices
PHENYL CARBAMATERelated product price
- PHENYL CARBAMATE
₹5044.45-22093.83 - PI 828
₹15469.99 - LY 294002 HYDROCHLORIDE
₹10660-37350
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