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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Bicyclic compound >PLUMBAGIN

PLUMBAGIN

PLUMBAGIN Structure
  • ₹2304 - ₹14234.88
  • Product name: PLUMBAGIN
  • CAS: 481-42-5
  • MF: C11H8O3
  • MW: 188.18
  • EINECS:207-569-6
  • MDL Number:MFCD00001682
  • Synonyms:plumbagone ;1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene;Plumbagin (natural);PLUMBAGIN PRACTICAL GRADE;Plumbagin, 99+%;PLUMBAGIN(RG);1,4-NAPHTHALENEDIONE,5-HYDROXY-2-METHYL;PLANT STEROLS KIT
Price7 Properties Safety Information Description
7 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 100MG
  • 250MG
  • 1gm
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1139
  • Product descriptionPlumbagin
  • Packaging1G
  • Price₹10000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7262
  • Product descriptionPlumbagin from Plumbago indica
  • Packaging100MG
  • Price₹2662.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7262
  • Product descriptionPlumbagin from Plumbago indica
  • Packaging250MG
  • Price₹5163.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7262
  • Product descriptionPlumbagin from Plumbago indica
  • Packaging1G
  • Price₹14234.88
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number P 4813
  • Product descriptionPlumbagin, from plumbago indica
  • Packaging100mg
  • Price₹2304
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 4813
  • Product descriptionPlumbagin, from plumbago indica
  • Packaging250mg
  • Price₹4608
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 4813
  • Product descriptionPlumbagin, from plumbago indica
  • Packaging1gm
  • Price₹12708
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1139 Plumbagin 1G ₹10000 2022-05-26 Buy
Sigma-Aldrich(India) P7262 Plumbagin from Plumbago indica 100MG ₹2662.95 2022-06-14 Buy
Sigma-Aldrich(India) P7262 Plumbagin from Plumbago indica 250MG ₹5163.53 2022-06-14 Buy
Sigma-Aldrich(India) P7262 Plumbagin from Plumbago indica 1G ₹14234.88 2022-06-14 Buy
ottokemi P 4813 Plumbagin, from plumbago indica 100mg ₹2304 2022-05-26 Buy
ottokemi P 4813 Plumbagin, from plumbago indica 250mg ₹4608 2022-05-26 Buy
ottokemi P 4813 Plumbagin, from plumbago indica 1gm ₹12708 2022-05-26 Buy

Properties

Melting point :76-78 °C(lit.)
Boiling point :283.17°C (rough estimate)
Density :1.354
refractive index :1.6310 (estimate)
storage temp. :-20°C
solubility :very faint turbidity in hot Methanol
pka :6.70±0.20(Predicted)
form :Crystals or Crystalline Powder
color :Orange
Merck :7538
Stability :Hygroscopic
LogP :2.450 (est)
EPA Substance Registry System :1,4-Naphthalenedione, 5-hydroxy-2-methyl- (481-42-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Plumbagin is a natural 1,4-naphthoquinone first isolated from plants of the genus Plumbago. It has diverse effects in cells and animals. Plumbagin causes the generation of reactive oxygen species and induces apoptosis in cancer cells. It activates signaling through Nrf2 and the antioxidant response element, inducing the expression of Nrf2 target genes, including NQO1 and heme oxygenase-1 in cultured neuronal cells. Plumbagin also inhibits NADPH oxidase 4 in a time- and dose-dependent manner. It can be protective against peroxide stress or deprivation of glucose or oxygen.

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Suppliers and manufacturers

GLR Innovations Biosyn Research Chemicals Otto Chemie Pvt Ltd CHEMAZON LABORATORIES AVIGYABIOSCIENCES PRIVATE LIMITED Biosyn Research Chemicals A.J Chemicals CLEARSYNTH LABS LTD. Otto Chemie Pvt. Ltd. TCI Chemicals (India) Pvt. Ltd.