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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Aromatic ketones >Phloretin

Phloretin

Phloretin Structure
  • ₹2304 - ₹67509
  • Product name: Phloretin
  • CAS: 60-82-2
  • MF: C15H14O5
  • MW: 274.27
  • EINECS:200-488-7
  • MDL Number:MFCD00002288
  • Synonyms:2,4,6-Trihydroxy-B-(4-Hydroxyphenyl)Propiophenone;Phloretin,98%;β-(4-hydroxyphenyl)-2,4,6-trihydroxypropiophenone;PHLORETIN(RG);1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-;trihydroxyphenyl)-;β-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone, 2μ,4μ,6μ-Trihydroxy-3-(4-hydroxyphenyl)propiophenone;2',4,4',6'-Tetrahydroxy-α,β-dihydro-trans-chalcone
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 10MG
  • 25mg
  • 100mg
  • 200MG
  • 250MG
  • 500mg
  • 1gm
  • 1G
  • 5gm
  • 5G
  • 25gm
  • ManufacturerALFA India
  • Product numberALF-L10991-MB
  • Product descriptionPhloretin, 98%
  • Packaging25mg
  • Price₹3189
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L10991-MC
  • Product descriptionPhloretin, 98%
  • Packaging100mg
  • Price₹4975
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1966
  • Product descriptionPhloretin
  • Packaging1G
  • Price₹10900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1966
  • Product descriptionPhloretin
  • Packaging5G
  • Price₹18000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number91897
  • Product descriptionPhloretin analytical standard
  • Packaging10MG
  • Price₹7750.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7912
  • Product descriptionPhloretin ≥99%
  • Packaging25MG
  • Price₹7772.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7912
  • Product descriptionPhloretin ≥99%
  • Packaging100MG
  • Price₹12253.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number524488
  • Product descriptionPhloretin - CAS 60-82-2 - Calbiochem A cell-permeable inhibtor of protein kinase C (IC?? = 20-50 μM).
  • Packaging200MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7912
  • Product descriptionPhloretin ≥99%
  • Packaging250MG
  • Price₹24670.18
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number P 1716
  • Product descriptionPhloretin, 99%
  • Packaging25mg
  • Price₹2304
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1716
  • Product descriptionPhloretin, 99%
  • Packaging100mg
  • Price₹7407
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1719
  • Product descriptionPhloretin 98%
  • Packaging1gm
  • Price₹9027
  • Updated2022-05-26
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  • Manufacturerottokemi
  • Product number P 1719
  • Product descriptionPhloretin 98%
  • Packaging5gm
  • Price₹13509
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1716
  • Product descriptionPhloretin, 99%
  • Packaging500mg
  • Price₹20079
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1716
  • Product descriptionPhloretin, 99%
  • Packaging1gm
  • Price₹30699
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1719
  • Product descriptionPhloretin 98%
  • Packaging25gm
  • Price₹67509
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-L10991-MB Phloretin, 98% 25mg ₹3189 2022-05-26 Buy
ALFA India ALF-L10991-MC Phloretin, 98% 100mg ₹4975 2022-05-26 Buy
TCI Chemicals (India) P1966 Phloretin 1G ₹10900 2022-05-26 Buy
TCI Chemicals (India) P1966 Phloretin 5G ₹18000 2022-05-26 Buy
Sigma-Aldrich(India) 91897 Phloretin analytical standard 10MG ₹7750.7 2022-06-14 Buy
Sigma-Aldrich(India) P7912 Phloretin ≥99% 25MG ₹7772.35 2022-06-14 Buy
Sigma-Aldrich(India) P7912 Phloretin ≥99% 100MG ₹12253.9 2022-06-14 Buy
Sigma-Aldrich(India) 524488 Phloretin - CAS 60-82-2 - Calbiochem A cell-permeable inhibtor of protein kinase C (IC?? = 20-50 μM). 200MG ₹15469.99 2022-06-14 Buy
Sigma-Aldrich(India) P7912 Phloretin ≥99% 250MG ₹24670.18 2022-06-14 Buy
ottokemi P 1716 Phloretin, 99% 25mg ₹2304 2022-05-26 Buy
ottokemi P 1716 Phloretin, 99% 100mg ₹7407 2022-05-26 Buy
ottokemi P 1719 Phloretin 98% 1gm ₹9027 2022-05-26 Buy
ottokemi P 1719 Phloretin 98% 5gm ₹13509 2022-05-26 Buy
ottokemi P 1716 Phloretin, 99% 500mg ₹20079 2022-05-26 Buy
ottokemi P 1716 Phloretin, 99% 1gm ₹30699 2022-05-26 Buy
ottokemi P 1719 Phloretin 98% 25gm ₹67509 2022-05-26 Buy

Properties

Melting point :~260 °C
Boiling point :337.26°C (rough estimate)
Density :1.1827 (rough estimate)
FEMA :4390 | 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE
refractive index :1.573-1.575
storage temp. :2-8°C
solubility :Acetonitrile (Slightly), Methanol (Slightly)
pka :7.16±0.40(Predicted)
form :Powder
color :White to beige
Odor :odorless
Water Solubility :soluble
Merck :14,7326
JECFA Number :2022
BRN :1887240
InChIKey :VGEREEWJJVICBM-UHFFFAOYSA-N
LogP :3.50
CAS DataBase Reference :60-82-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phloretin is a natural phenol which inhibits a variety of transporters. It inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 μM, respectively), restricting the rapid transport of monocarboxylates like lactate and pyruvate across the plasma membrane. Phloretin also blocks the sodium/D-glucose cotransporter (Ki = 86 μM) and the human concentrative nucleoside transporter 3 (Ki = 32 μM).

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