Quinagolide hydrochloride
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- Product name: Quinagolide hydrochloride
- CAS: 94424-50-7
- MF: C20H34ClN3O3S
- MW: 432.02
- EINECS:
- MDL Number:MFCD00893553
- Synonyms:QUINAGOLIDE HYDROCHLORIDE;(3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride;(3α,4aα,10aβ)-N,N-Diethyl-N'-
(1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride;Norprolac Hydrochloride;rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride;SDZ 205-502;Quinagolide hydrochloride (CV205-502 hydrochloride);(+/-)-N,N-diethyl-N'-<(3α,4aα,10aβ)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzo
quinolinyl>sulfamide hydrochloride
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Properties
Melting point :234-236°
storage temp. :Store at -20°C
solubility :DMSO : ≥ 43 mg/mL (99.53 mM)
form :Solid
color :White to off-white
CAS DataBase Reference :94424-50-7(CAS DataBase Reference)
storage temp. :Store at -20°C
solubility :DMSO : ≥ 43 mg/mL (99.53 mM)
form :Solid
color :White to off-white
CAS DataBase Reference :94424-50-7(CAS DataBase Reference)
Safety Information
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Description
Quinagolide is a potent and specific non-ergot dopamine D2 agonist launched in the Netherlands for the treatment of hyperprolactinemia. Quinagolide is effective in inhibiting prolactin secretion by human pituitary tumor and hyperprolactinemia in vitro and in viva A daily dose of as low as 60 pg is able to achieve a pronounced and prolonged suppressive effect on serum prolactin and growth hormone secretion. It is also effective in providing relief from associated effects such as infertility, galactorrhea, oligomenorrhea, amenorrhea, loss of IibMo and impotence. Compared with the most widely used antiprolactin, bromocriptine, quinagolide is more potent in vivo with a longer duration of action and fewer side effects. A recent study showed that acute administration of quinagolide suppresses growth hormone secretion in acromegalic patients and thus could serve as an alternative therapy in acromegaly.More related product prices
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Suppliers and manufacturers
CLEARSYNTH LABS LTD.
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.
AFINE CHEMICALS LIMITED
Hangzhou MolCore BioPharmatech Co.,Ltd.
Amadis Chemical Company Limited
Shanghai Hao Zhun Biological Technology Co., Ltd.
Shanghai Ziqi Biological Technology Co., Ltd.
Shanghai Hao Biological Technology Co., Ltd.
Shanghai Yubo Biotechnology Co., Ltd.