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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Angiogenesis >BTK inhibitors >RN486

RN486

RN486 Structure
  • ₹0
  • Product name: RN486
  • CAS: 1242156-23-5
  • MF: C35H35FN6O3
  • MW: 606.69
  • EINECS:200-110-4
  • MDL Number:MFCD24682729
  • Synonyms:RN486;6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-((5-(4-Methylpiperazin-1-yl)pyridin-2-yl)aMiNA)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquiNAlin-1(2H)-one;6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-(5-(4-Methylpiperazin-1-yl)pyridin-2-ylaMino)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquinolin-1(2H)-one;RN486/RN-486;RN468;6-Cyclopropyl-2-[3-[1,6-dihydro-1-methyl-5-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-(hydroxymethyl)phenyl]-8-fluoro-1(2H)-isoquinolinone;RN486 LM-2078;RN486 TFA Salt
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :868.6±65.0 °C(Predicted)
Density :1.378±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥30.35 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :solid
pka :13.95±0.10(Predicted)
color :Off-white to light yellow
CAS DataBase Reference :1242156-23-5

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

RN 486 is a Bruton’s tyrosine kinase (Btk) inhibitor, blocking receptor cross-linking-induced degranulation in mast cells. May be used in the prevention of arthritis and other autoimmune diseases.

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Suppliers and manufacturers

career henan chemical co
RN486
₹1.00 /1KG
RN486 CAS: 1242156-23-5
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
ROSEWA HOLDING GROUP CO.,LIMITED
Amadis Chemical Company Limited