RO 48-8071
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- ₹10670
- Product name: RO 48-8071
- CAS: 189197-69-1
- MF: C23H27BrFNO2.C4H4O4
- MW: 564.45
- EINECS:
- MDL Number:MFCD05865242
- Synonyms:Ro 48-8071 fumarate salt;(4-((6-(allyl(methyl)amino)hexyl)oxy)-2-fluorophenyl)(4-bromophenyl)methanone fumarate Ro48-8071;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone (2E)-2-butenedioate (1:1);OSC Inhibitor, Ro 48-8071 ;Aids163155;Aids-163155;Methanone, (4-bromophenyl)[2-fluoro-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl]-,(2E)-2-butenedioate;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
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Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- ManufacturerSigma-Aldrich(India)
- Product number499635
- Product descriptionOSC Inhibitor, Ro 48-8071 - CAS 189197-69-1 - Calbiochem The OSC Inhibitor, Ro 48-8071, also referenced under CAS 189197-69-1, controls the biological activity of 2,3-oxidosqualene:lanosterol cyclase activit
- Packaging10MG
- Price₹10670
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 499635 | OSC Inhibitor, Ro 48-8071 - CAS 189197-69-1 - Calbiochem The OSC Inhibitor, Ro 48-8071, also referenced under CAS 189197-69-1, controls the biological activity of 2,3-oxidosqualene:lanosterol cyclase activit | 10MG | ₹10670 | 2022-06-14 | Buy |
Properties
Melting point :90-92.7 °C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >5 mg/mL at ~60 °C
form :solid
color :white
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >5 mg/mL at ~60 °C
form :solid
color :white
Safety Information
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Description
Ro 48-8071 fumarate is an orally active 2,3-oxidosqualene lanosterol cyclase (OSC) inhibitor where OSC represents a unique target for a cholesterol-lowering drug. Partial inhibition of OSC should reduce synthesis of lanosterol and subsequent sterols, and also stimulate the production of epoxysterols that repress HMG-CoA reductase expression, generating a synergistic, self-limited negative regulatory loop.Related product price
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