SC-514
- ₹8584.23 - ₹34737.43
- Product name: SC-514
- CAS: 354812-17-2
- MF: C9H8N2OS2
- MW: 224.3
- EINECS:
- MDL Number:MFCD00206459
- Synonyms:SC-514, >=98%;3-amino-5-(thiophen-3-yl)thiophene-2-carboxamide;SC-514;GK 01140;IKK-2 Inhibitor, SC-514 ;4-Amino-[2',3'-bithiophene]-5-carboxamide;SC-514;5-(Thien-3-yl)-3-aminothiophene-2-carboxamide;GK 01140
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0557
- Product descriptionSC-514 ≥97% (HPLC)
- Packaging5MG
- Price₹8584.23
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number401479
- Product descriptionIKK-2 Inhibitor, SC-514 - CAS 354812-17-2 - Calbiochem The IKK-2 Inhibitor, SC-514, also referenced under CAS 354812-17-2, controls the biological activity of IKK-2. This small molecule/inhibitor is primar
- Packaging1MG
- Price₹14260
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0557
- Product descriptionSC-514 ≥97% (HPLC)
- Packaging25MG
- Price₹34737.43
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0557 | SC-514 ≥97% (HPLC) | 5MG | ₹8584.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 401479 | IKK-2 Inhibitor, SC-514 - CAS 354812-17-2 - Calbiochem The IKK-2 Inhibitor, SC-514, also referenced under CAS 354812-17-2, controls the biological activity of IKK-2. This small molecule/inhibitor is primar | 1MG | ₹14260 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0557 | SC-514 ≥97% (HPLC) | 25MG | ₹34737.43 | 2022-06-14 | Buy |
Properties
Melting point :209-211°C
Boiling point :399.2±42.0 °C(Predicted)
Density :1.450±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :15.63±0.50(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :399.2±42.0 °C(Predicted)
Density :1.450±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :15.63±0.50(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
SC-514 is a selective and reversible inhibitor of IKKβ (IKK-2) (IC50 = 3-12 μM) that displays >10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. This compound attenuates NF-κB-induced gene expression of IL-6, IL-8 and Cox-2 (IC50 = 20, 20, and 8 μM, respectively). Improper activation of NF-κB has been linked to cancer, immune and inflammatory diseases, and viral infection.Related product price
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