BAY 11-7082
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- ₹9700 - ₹15003.45
- Product name: BAY 11-7082
- CAS: 19542-67-7
- MF: C10H9NO2S
- MW: 207.25
- EINECS:
- MDL Number:MFCD00712162
- Synonyms:BAY 11-7082;BAY 11-7821;(E)-3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE;(E)-3-tosylacrylonitrile;(E)-3-(p-Toluenesulfonyl)acrylonitrile;BAY11-7082/BAY117082;BAY11-7082,BAY 117821;(2E)-3-[(4-METHYLPHENYL)SULFONYL]-2-PROPENENITRILE
5 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
- Sigma-Aldrich
Package
- 10MG
- 100MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberT2846
- Product descriptionBAY 11-7082
- Packaging100MG
- Price₹9700
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberT2846
- Product descriptionBAY 11-7082
- Packaging1G
- Price₹14500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberB5556
- Product descriptionBay 11-7082 ≥98% (HPLC), powder
- Packaging10MG
- Price₹15003.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number196870
- Product descriptionBAY 11-7082 - CAS 19542-67-7 - Calbiochem The BAY 11-7082, also referenced under CAS 19542-67-7, controls the biological activity of TNF-α. This small molecule/inhibitor is primarily used for
- Packaging10MG
- Price₹12969.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich
- Product number196870
- Product descriptionBAY 11-7082 - CAS 19542-67-7 - Calbiochem The BAY 11-7082, also referenced under CAS 19542-67-7, controls the biological activity of TNF-α. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
- Packaging10MG
- Price₹12969.99
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | T2846 | BAY 11-7082 | 100MG | ₹9700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T2846 | BAY 11-7082 | 1G | ₹14500 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | B5556 | Bay 11-7082 ≥98% (HPLC), powder | 10MG | ₹15003.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 196870 | BAY 11-7082 - CAS 19542-67-7 - Calbiochem The BAY 11-7082, also referenced under CAS 19542-67-7, controls the biological activity of TNF-α. This small molecule/inhibitor is primarily used for | 10MG | ₹12969.99 | 2022-06-14 | Buy |
| Sigma-Aldrich | 196870 | BAY 11-7082 - CAS 19542-67-7 - Calbiochem The BAY 11-7082, also referenced under CAS 19542-67-7, controls the biological activity of TNF-α. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications. | 10MG | ₹12969.99 | 2022-06-14 | Buy |
Properties
Melting point :133-135℃
Boiling point :397.6±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: 25 mg/mL, soluble
form :solid
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :397.6±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: 25 mg/mL, soluble
form :solid
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
BAY 11-7082, a potential anti-inflammatory agent, is an irreversible inhibitor of IKK α and phosphorylation of cytokine-inducible IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-α, NFKBIA; IC50=10 μM). In intact HUVECs, it inhibits TNFα-induced phosphorylation and degradation of IκBa (NFKBIA) without affecting constitutive phosphorylation. Inhibition of ιBα phosphorylation and degradation results in the inactivation of NFκB and thereby inhibits the expression of endothelial-leukocyte adhesion molecules: E-selectin, VCAM-1 and ICAM-11. BAY 11-7082 has also demonstrated stimulation of the stress-activated protein kinases, p38 and JNK-1.Related product price
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