ROCAGLAMIDE
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- ₹36545.2
- Product name: ROCAGLAMIDE
- CAS: 84573-16-0
- MF: C29H31NO7
- MW: 505.56
- EINECS:
- MDL Number:MFCD08702699
- Synonyms:ROCAGLAMIDE;(1R)-2,3,3a,8b-Tetrahydro-1α,8bβ-dihydroxy-6,8-dimethoxy-3aβ-(4-methoxyphenyl)-N,N-dimethyl-3β-phenyl-1H-cyclopenta[b]benzofuran-2α-carboxamide;(1R)-N,N-Dimethyl-1α,8bβ-dihydroxy-3β-phenyl-3aβ-(4-methoxyphenyl)-6,8-dimethoxy-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2α-carboxamide;2,3,3a,8b-Tetrahydro-1α,8bβ-dihydroxy-6,8-dimethoxy-3aβ-(4-methoxyphenyl)-N,N-dimethyl-3β-phenyl-1H-cyclopenta[b]benzofuran-2α-carboxamide;2,3,3a,8b-Tetrahydro-N,N-dimethyl-1α,8bβ-dihydroxy-6,8-dimethoxy-3β-phenyl-3aβ-(4-methoxyphenyl)-1H-cyclopenta[b]benzofuran-2α-carboxamide;N,N-Dimethyl-1α,8bβ-dihydroxy-6,8-dimethoxy-3β-phenyl-3aβ-(4-methoxyphenyl)-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2α-carboxamide;(1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide;NSC 326408
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 100μG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0656
- Product descriptionRocaglamide ≥96% (HPLC)
- Packaging100μG
- Price₹36545.2
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0656 | Rocaglamide ≥96% (HPLC) | 100μG | ₹36545.2 | 2022-06-14 | Buy |
Properties
Melting point :117-118 °C
Boiling point :667.3±55.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO or Ethanol
form :film
pka :11.70±0.70(Predicted)
color :colorless
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. Protect from exposure to light and moisture.
Boiling point :667.3±55.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO or Ethanol
form :film
pka :11.70±0.70(Predicted)
color :colorless
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. Protect from exposure to light and moisture.
Safety Information
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Description
Rocaglamide is an anti-inflammatory, insecticidal, and anticancer tetrahydrobenzofuran isolated from Aglaia species. It has been shown to inhibit both TNF-α and the activation of NF-κB in Jurkat T cells with IC50 values in the nanomolar range. At 25 nM, rocaglamide induces apoptosis in various human leukemia cell lines, activating p38 MAPK/JNK and suppressing ERK. Rocaglamide also reduces IFN-γ, TNF-α, IL-2, and IL-4 production in peripheral blood T cells at a concentration of 50 nM. Furthermore, rocaglamide can inhibit the T cell expression of the immune response transcription factor, nuclear factor of activated T cells.More related product prices
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