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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >SINOMENINE HYDROCHLORIDE

SINOMENINE HYDROCHLORIDE

SINOMENINE HYDROCHLORIDE Structure
  • ₹8100 - ₹25900
  • Product name: SINOMENINE HYDROCHLORIDE
  • CAS: 6080-33-7
  • MF: C19H24ClNO4
  • MW: 365.85
  • EINECS:618-347-7
  • MDL Number:MFCD01714307
  • Synonyms:(9a,13a,14a)-4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride;SINOMENINE HYDROCHLORIDE;SINOMENINE HCL;(9α,13α,14α)- 7,8-Didehydro-4- hydroxy-3,7-diMet;7,8-Didehydro-4-hydroxy-3,7-diMethoxy-17-Methyl- 9α,13α,14α-Morphinan-6-one Hydrochloride;Tuduranine Hydrochloride;hydroxy-dimethoxy-methyl-BLAH-azatetracyclo[BLAH]hexadeca-BLAH,BLAH,BLAH,BLAH-tetraenone;Sinomenine Hydrocloride
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberS0926
  • Product descriptionSinomenine Hydrochloride
  • Packaging1G
  • Price₹8100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberS0926
  • Product descriptionSinomenine Hydrochloride
  • Packaging5G
  • Price₹25900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1002
  • Product descriptionSinomenine hydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹11528.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) S0926 Sinomenine Hydrochloride 1G ₹8100 2022-05-26 Buy
TCI Chemicals (India) S0926 Sinomenine Hydrochloride 5G ₹25900 2022-05-26 Buy
Sigma-Aldrich(India) SML1002 Sinomenine hydrochloride ≥98% (HPLC) 50MG ₹11528.63 2022-06-14 Buy

Properties

Melting point :231.0 to 235.0 °C
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: soluble20mg/mL, clear
form :powder
color :white to beige
optical activity :[α]/D -70 to -90°, c = 1 in H2O
Water Solubility :Soluble to 100 mM in water

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Sinomenine is a natural plant alkaloid commonly used to alleviate inflammation associated with rheumatoid arthritis. It activates histamine release, reduces joint stiffness and pain, and alters cytokine generation without producing gastrointestinal adverse events. Sinomenine also impairs signaling through NF-κB, resulting in immunosuppression as well as reduced inflammation and pain. It enhances the bioavailability of some compounds, at least in part through an inhibition of drug export by transporters like P-glycoprotein.

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