Terbinafine Hydrochloride
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- ₹6500 - ₹28600
- Product name: Terbinafine Hydrochloride
- CAS: 78628-80-5
- MF: C21H26ClN
- MW: 327.89
- EINECS:616-640-4
- MDL Number:MFCD00145430
- Synonyms:Terbinafine hydrochloride, >=98%;Terbinafinehydrochloride(GMP);terbinafine hydrochloride, N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride;1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1);Terbinafine Hydrochioride Tablets;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon ;TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine monohydrochloride
5 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 100MG
- 250MG
- 1G
- 5G
- ManufacturerTCI Chemicals (India)
- Product numberD2049
- Product descriptionTerbinafine Hydrochloride
- Packaging1G
- Price₹6500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberD2049
- Product descriptionTerbinafine Hydrochloride
- Packaging5G
- Price₹28600
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1298
- Product descriptionTerbinafine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹8356.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT8826
- Product descriptionTerbinafine hydrochloride
- Packaging100MG
- Price₹12091.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT8826
- Product descriptionTerbinafine hydrochloride
- Packaging250MG
- Price₹17016.9
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D2049 | Terbinafine Hydrochloride | 1G | ₹6500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D2049 | Terbinafine Hydrochloride | 5G | ₹28600 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | PHR1298 | Terbinafine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹8356.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8826 | Terbinafine hydrochloride | 100MG | ₹12091.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8826 | Terbinafine hydrochloride | 250MG | ₹17016.9 | 2022-06-14 | Buy |
Properties
Melting point :204-208°C
storage temp. :15-25°C
solubility :methanol: soluble50mg/mL
form :powder
color :white
Merck :14,9156
BCS Class :1
InChI :InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChIKey :BWMISRWJRUSYEX-SZKNIZGXSA-N
SMILES :C12C=CC=CC1=CC=CC=2CN(C)C/C=C/C#CC(C)(C)C.Cl
CAS DataBase Reference :78628-80-5(CAS DataBase Reference)
storage temp. :15-25°C
solubility :methanol: soluble50mg/mL
form :powder
color :white
Merck :14,9156
BCS Class :1
InChI :InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChIKey :BWMISRWJRUSYEX-SZKNIZGXSA-N
SMILES :C12C=CC=CC1=CC=CC=2CN(C)C/C=C/C#CC(C)(C)C.Cl
CAS DataBase Reference :78628-80-5(CAS DataBase Reference)
Safety Information
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Description
Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis. Research has shown that Terbinafine also reduces the ability of fungal pathogens to generate reactive oxygen species, therefore it is noted as a free radical scavenger in vitro and could potentially contain anti-inflammatory activity in vivo. Additionally, Terbinafine has also been reported to suppress cell proliferation in vitro and in vivo through inhibition of DNA synthesis and apoptosis activation. It has also been noted that by pretreating of cells with a p21 specific antisense oligonucleotide the Terbinafine induced inhibition of cell growth can be reversed. Assays further demonstrated that Terbinafine also contains anti-angiogenic effects in chick embryo chorioallantoic membranes. We provide this product in the hydrochloride form.More related product prices
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