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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cytoskeletal Signaling >Microtubule Associated inhibitors >Triclabendazole

Triclabendazole

Triclabendazole Structure
  • ₹9200 - ₹19800
  • Product name: Triclabendazole
  • CAS: 68786-66-3
  • MF: C14H9Cl3N2OS
  • MW: 359.66
  • EINECS:614-728-7
  • MDL Number:MFCD00864519
  • Synonyms:FASINEX;CGA-89317;5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE;TRICLABENDAZOLE;5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol ;5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex;1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-;5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-(METHYLTHIO)-1H-BENZIMIDAZOL(TRICLABENDAZOLE)
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberT2826
  • Product descriptionTriclabendazole
  • Packaging1G
  • Price₹9200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2826
  • Product descriptionTriclabendazole
  • Packaging5G
  • Price₹19800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number32802
  • Product descriptionTriclabendazole VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹17698.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T2826 Triclabendazole 1G ₹9200 2022-05-26 Buy
TCI Chemicals (India) T2826 Triclabendazole 5G ₹19800 2022-05-26 Buy
Sigma-Aldrich(India) 32802 Triclabendazole VETRANAL?, analytical standard 100MG ₹17698.88 2022-06-14 Buy

Properties

Melting point :175-176°C
Boiling point :240.6°C (rough estimate)
Density :1.3875 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Acetonitrile (Slightly, Sonicated), Methanol (Slightly)
form :Solid
pka :7.91±0.10(Predicted)
color :White to Beige
Merck :14,9652
BCS Class :4/3
Stability :Stability
InChI :InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
InChIKey :NQPDXQQQCQDHHW-UHFFFAOYSA-N
SMILES :C1(SC)NC2=CC(Cl)=C(OC3=CC=CC(Cl)=C3Cl)C=C2N=1
CAS DataBase Reference :68786-66-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Triclabendazole is a member of the benzimidazole family of anthelmintics. It is effective against F. hepatica helminths that cause fascioliasis, reducing secreted protease enzyme activities that are critical for the invasion, migration, nutrition, and survival of the parasite. In yeast and mammalian cells, triclabendazole was shown to inhibit adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A nutrient-sensing pathway and to prevent apoptosis induced by the Parkinson’s disease-related protein α-synuclein, demonstrating a protective role during various cellular stresses.

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Suppliers and manufacturers

NGL Fine Chem limited RP Industries THE MOLECULEZ Saptagir Laboratories PVT.LTD. SNECOFRi Pvt Ltd Reenold Enterprises Cefa-Cilinas Biotics Pvt Ltd Murli Krishna Exports Pvt Ltd Siflon Drugs Chemino Pharma Ltd