VEGFR2 Kinase Inhibitor I
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- Product name: VEGFR2 Kinase Inhibitor I
- CAS: 15966-93-5
- MF: C18H18N2O3
- MW: 310.35
- EINECS:-0
- MDL Number:
- Synonyms:SU5408;VEGFR2 KISE INHIBITOR I;VEGFR2 Kinase Inhibitor I;VEGFR2 TK Inhibitor;SU 5408;SU-5408;SU5408;VEGFR2 kinase inhibitor I(SU-5408);1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester;Research Grade Ramucirumab(DHE16601)
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Properties
Boiling point :571.4±50.0 °C(Predicted)
Density :1.271±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml
form :A crystalline solid
pka :12.40±0.20(Predicted)
color :Yellow to orange
Density :1.271±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml
form :A crystalline solid
pka :12.40±0.20(Predicted)
color :Yellow to orange
Safety Information
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Description
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2 kinase (IC50 = 70 nM). It has little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC50 > 100 μM).More related product prices
DEMETON S NSC 247030 SU 5205 IC 261 1055412-47-9 SU 5214 SU 9516 SU 5416Related product price
- IC 261
₹7300-17860 - 1055412-47-9
₹15458.1-58844.7 - SU 5416
₹13163.2-52663.63
