SU 5416
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- ₹13163.2 - ₹52663.63
- Product name: SU 5416
- CAS: 204005-46-9
- MF: C15H14N2O
- MW: 238.28
- EINECS:200-256-5
- MDL Number:MFCD01940922
- Synonyms:H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-;SeMaxinib;SU 5416 (SeMaxinib);SU5416 /SU-5416;(Z)-3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one;3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one;3-[(3,5-diMethyl-1H-pyrrol-2-yl)Methylidene]-1H-indol-2-one;SEMAXINIB(SU 5416)
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberS8442
- Product descriptionSU 5416 ≥98% (HPLC)
- Packaging5MG
- Price₹13163.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS8442
- Product descriptionSU 5416 ≥98% (HPLC)
- Packaging25MG
- Price₹52663.63
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S8442 | SU 5416 ≥98% (HPLC) | 5MG | ₹13163.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S8442 | SU 5416 ≥98% (HPLC) | 25MG | ₹52663.63 | 2022-06-14 | Buy |
Properties
Melting point :226-228 °C
Boiling point :481.4±45.0 °C(Predicted)
Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: insoluble
pka :12.59±0.20(Predicted)
form :Yellow orange solid
color :yellow to yellow orange
Boiling point :481.4±45.0 °C(Predicted)
Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: insoluble
pka :12.59±0.20(Predicted)
form :Yellow orange solid
color :yellow to yellow orange
Safety Information
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Description
SU 5416 is a tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR2; FLK1/KDR) and a suppressor of tumor vascularization, preventing the growth of multiple tumor types. In addition to inhibiting VEGFR2 (IC50 = 1 μM), SU 5416 also inhibits PDGFR (IC50 = 20 μM), c-Kit (IC50 = 30 nM), RET (IC50 = 170 nM), FLT3 (IC50 = 160 nM), ABL (IC50 = 11 μM), and ALK (IC50 = 1.2 μM). SU 5416 does not inhibit epidermal growth factor or fibroblast growth factor receptor tyrosine kinases (IC50 > 100 μM).More related product prices
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