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WWL229

WWL229 Structure
  • ₹11528.63 - ₹46515.03
  • Product name: WWL229
  • CAS: 1338575-28-2
  • MF: C16H22N2O5
  • MW: 322.36
  • EINECS:
  • MDL Number:MFCD28160858
  • Synonyms:WWL229;XVBRVSAGMWRVCK-UHFFFAOYSA-N;Reaxys ID: 25732135;1-Piperidinecarboxylic acid, 2-(3-methoxypropyl)-, 4-nitrophenyl ester;WWL229 4-Nitrophenyl 2-(3-methoxypropyl) piperidine-1-carboxylate;WWL 229,WWL-229,Inhibitor,inhibit,WWL229
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1180
  • Product descriptionWWL229 ≥98% (HPLC)
  • Packaging5MG
  • Price₹11528.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1180
  • Product descriptionWWL229 ≥98% (HPLC)
  • Packaging25MG
  • Price₹46515.03
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1180 WWL229 ≥98% (HPLC) 5MG ₹11528.63 2022-06-14 Buy
Sigma-Aldrich(India) SML1180 WWL229 ≥98% (HPLC) 25MG ₹46515.03 2022-06-14 Buy

Properties

storage temp. :2-8°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :oil
color :colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Mouse carboxylesterase 3 (Ces3, also named Ces1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation. Although important for basal lipolysis, Ces3 expression can be induced by xenobiotics. Ces3 activity is significantly elevated during adipocyte differentiation. WWL229 is a selective inhibitor of Ces3 (IC50 = 1.94 μM) that has no significant effect on other, related enzymes. By inhibiting the triglyceride hydrolase activity of Ces3, WWL229 promotes lipid storage in cultured adipocytes and prevents basal lipolysis.

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