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Wnt Agonist

Wnt Agonist Structure
  • ₹11419.99 - ₹46374.3
  • Product name: Wnt Agonist
  • CAS: 853220-52-7
  • MF: C19H18N4O3
  • MW: 350.37
  • EINECS:
  • MDL Number:MFCD09908087
  • Synonyms:AMBMP;CID 11210285 hydrochloride;N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride;Wnt agonist 1;BML-284;2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine hydrochloride;Wnt agonist 1 (BML-284);N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine
4 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 2MG
  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product number681664
  • Product descriptionWnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily
  • Packaging2MG
  • Price₹11419.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0698
  • Product descriptionCID 11210285 hydrochloride ≥98% (HPLC)
  • Packaging5MG
  • Price₹11506.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number681665
  • Product descriptionWnt Agonist - CAS 853220-52-7 - Calbiochem The Wnt Agonist, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for C
  • Packaging5MG
  • Price₹25950
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0698
  • Product descriptionCID 11210285 hydrochloride ≥98% (HPLC)
  • Packaging25MG
  • Price₹46374.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 681664 Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily 2MG ₹11419.99 2022-06-14 Buy
Sigma-Aldrich(India) SML0698 CID 11210285 hydrochloride ≥98% (HPLC) 5MG ₹11506.98 2022-06-14 Buy
Sigma-Aldrich(India) 681665 Wnt Agonist - CAS 853220-52-7 - Calbiochem The Wnt Agonist, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for C 5MG ₹25950 2022-06-14 Buy
Sigma-Aldrich(India) SML0698 CID 11210285 hydrochloride ≥98% (HPLC) 25MG ₹46374.3 2022-06-14 Buy

Properties

Boiling point :623.4±65.0 °C(Predicted)
Density :1.353±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :6.62±0.10(Predicted)
form :Yellowish sticky solid
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Wnt Agonist is a cell-permeable pyrimidine compound that acts as, at an IC50 > 60 μM, a potent and selective activator of Wnt signaling. In addition to mimicking the effect of Wnt, Wnt Agonist has also induced β-catenin and T-cell fate-dependent transcriptional activity in HEK-293T cells at an EC50 = 700 nM. When applied to Xenopous embryos Wnt Agonist caused substantial head defects development. Wnt Agonist has also been observed to enhance beta cell expansion in vitro. The compound is beneficial for studying the effects of Wnt pathway due to the activation of Wnt without inhibiting the activity of GSK-3β.

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