Actinomycin D
- ₹4384.13 - ₹121283.3
- Product name: Actinomycin D
- CAS: 50-76-0
- MF: C62H86N12O16
- MW: 1255.42
- EINECS:200-063-6
- MDL Number:MFCD00005033
- Synonyms:2-Amino-N,N'-bis[hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide;Actinomycin D, Actinomycin IV, Actinomycin C1, Dactinomycin;Dactinomycin, DTM;Actinomycin C1, Dactinomycin;Actactinomycin A IV;Cosmogen;actinomycin7 ;actinomycinaiv
16 prices
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Brand
- Sigma-Aldrich(India)
- SRL
Package
- 2MG
- 5MG
- 10MG
- 25MG
- 100MG
- 1ML
- ManufacturerSigma-Aldrich(India)
- Product numberA1410
- Product descriptionActinomycin D from Streptomyces sp., ~98% (HPLC)
- Packaging25MG
- Price₹42715.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9415
- Product descriptionActinomycin D from Streptomyces sp., suitable for cell culture, ≥95%
- Packaging10MG
- Price₹34704.95
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4262
- Product descriptionActinomycin D from Streptomyces sp., ≥95% (HPLC)
- Packaging25MG
- Price₹33081.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA1410
- Product descriptionActinomycin D from Streptomyces sp., ~98% (HPLC)
- Packaging10MG
- Price₹18510.75
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9415
- Product descriptionActinomycin D from Streptomyces sp., suitable for cell culture, ≥95%
- Packaging5MG
- Price₹17785.48
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSBR00013
- Product descriptionActinomycin D, Ready Made Solution from Streptomyces sp., 2?mg/mL in DMSO
- Packaging1ML
- Price₹15388.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA1410
- Product descriptionActinomycin D from Streptomyces sp., ~98% (HPLC)
- Packaging100MG
- Price₹121283.3
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9415
- Product descriptionActinomycin D from Streptomyces sp., suitable for cell culture, ≥95%
- Packaging25MG
- Price₹54103.35
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4262
- Product descriptionActinomycin D from Streptomyces sp., ≥95% (HPLC)
- Packaging10MG
- Price₹15165.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA1410
- Product descriptionActinomycin D from Streptomyces sp., ~98% (HPLC)
- Packaging5MG
- Price₹12275.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA1410
- Product descriptionActinomycin D from Streptomyces sp., ~98% (HPLC)
- Packaging2MG
- Price₹11387.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4262
- Product descriptionActinomycin D from Streptomyces sp., ≥95% (HPLC)
- Packaging5MG
- Price₹8822.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA9415
- Product descriptionActinomycin D from Streptomyces sp., suitable for cell culture, ≥95%
- Packaging2MG
- Price₹7772.35
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA4262
- Product descriptionActinomycin D from Streptomyces sp., ≥95% (HPLC)
- Packaging2MG
- Price₹4384.13
- Updated2022-06-14
- Buy
- ManufacturerSRL
- Product number28269
- Product descriptionActinomycin D (AMD) extrapure, 98%
- Packaging5mg
- Price₹13200
- Updated2022-05-26
- Buy
- ManufacturerSRL
- Product number28269
- Product descriptionActinomycin D (AMD) extrapure, 98%
- Packaging2mg
- Price₹5630
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A1410 | Actinomycin D from Streptomyces sp., ~98% (HPLC) | 25MG | ₹42715.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9415 | Actinomycin D from Streptomyces sp., suitable for cell culture, ≥95% | 10MG | ₹34704.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A4262 | Actinomycin D from Streptomyces sp., ≥95% (HPLC) | 25MG | ₹33081.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1410 | Actinomycin D from Streptomyces sp., ~98% (HPLC) | 10MG | ₹18510.75 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9415 | Actinomycin D from Streptomyces sp., suitable for cell culture, ≥95% | 5MG | ₹17785.48 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SBR00013 | Actinomycin D, Ready Made Solution from Streptomyces sp., 2?mg/mL in DMSO | 1ML | ₹15388.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1410 | Actinomycin D from Streptomyces sp., ~98% (HPLC) | 100MG | ₹121283.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9415 | Actinomycin D from Streptomyces sp., suitable for cell culture, ≥95% | 25MG | ₹54103.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A4262 | Actinomycin D from Streptomyces sp., ≥95% (HPLC) | 10MG | ₹15165.83 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1410 | Actinomycin D from Streptomyces sp., ~98% (HPLC) | 5MG | ₹12275.55 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1410 | Actinomycin D from Streptomyces sp., ~98% (HPLC) | 2MG | ₹11387.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A4262 | Actinomycin D from Streptomyces sp., ≥95% (HPLC) | 5MG | ₹8822.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9415 | Actinomycin D from Streptomyces sp., suitable for cell culture, ≥95% | 2MG | ₹7772.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A4262 | Actinomycin D from Streptomyces sp., ≥95% (HPLC) | 2MG | ₹4384.13 | 2022-06-14 | Buy |
SRL | 28269 | Actinomycin D (AMD) extrapure, 98% | 5mg | ₹13200 | 2022-05-26 | Buy |
SRL | 28269 | Actinomycin D (AMD) extrapure, 98% | 2mg | ₹5630 | 2022-05-26 | Buy |
Properties
Melting point :251-253 °C
Boiling point :848°C (rough estimate)
Density :1.0757 (rough estimate)
refractive index :1.5700 (estimate)
Flash point :87℃
storage temp. :2-8°C
solubility :ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble
pka :8.94±0.70(Predicted)
form :powder
color :red, powder
optical activity :[α]/D alpha: 28/D (Rotation: -315 degrees (c=0.25% in methanol))
Water Solubility :SOLUBLE
Merck :13,2828
BRN :605235
Stability :Stable, but light sensitive, especially in dilute solution. Incompatible with strong acids, strong bases, strong oxidizing agents. Combustible.
CAS DataBase Reference :50-76-0(CAS DataBase Reference)
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Actinomycin D (50-76-0)
Boiling point :848°C (rough estimate)
Density :1.0757 (rough estimate)
refractive index :1.5700 (estimate)
Flash point :87℃
storage temp. :2-8°C
solubility :ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble
pka :8.94±0.70(Predicted)
form :powder
color :red, powder
optical activity :[α]/D alpha: 28/D (Rotation: -315 degrees (c=0.25% in methanol))
Water Solubility :SOLUBLE
Merck :13,2828
BRN :605235
Stability :Stable, but light sensitive, especially in dilute solution. Incompatible with strong acids, strong bases, strong oxidizing agents. Combustible.
CAS DataBase Reference :50-76-0(CAS DataBase Reference)
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Actinomycin D (50-76-0)
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low concentrations (~10 nM), which interferes with RNA synthesis and ultimately leads to cell death. Actinomycin D is widely used as an anticancer agent for treating a variety of tumors and along with its fluorescent derivative, 7-aminoactinomycin D has become a useful tool in biochemistry and molecular biology research as a marker for DNA.Related product price
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