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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Adefovir

Adefovir

Adefovir Structure
  • ₹11555.1 - ₹45876.3
  • Product name: Adefovir
  • CAS: 106941-25-7
  • MF: C8H12N5O4P
  • MW: 273.19
  • EINECS:600-789-7
  • MDL Number:MFCD00866943
  • Synonyms:2-(6-amino-9h-purin-;Adefovir dipivox (PMEA);[[2-(6-AMino-9H-purin-9-yl)ethoxy] Methyl]phosponic Acid;P-[[2-(6-AMino-9H-purin-9-yl)ethoxy]Methyl]phosphonic Acid;Adefovir(PMEA);Adefovir98%;[({[2-(6-aMino-9H-purin-9-yl)ethoxy]Methyl}({[(2,2-diMethylpropanoyl)oxy]Methoxy})phosphoryl)oxy]Methyl 2,2-diMethylpropanoate;A Duff Vee
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0240
  • Product descriptionAdefovir ≥98% (HPLC)
  • Packaging10MG
  • Price₹11555.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0240
  • Product descriptionAdefovir ≥98% (HPLC)
  • Packaging50MG
  • Price₹45876.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0240 Adefovir ≥98% (HPLC) 10MG ₹11555.1 2022-06-14 Buy
Sigma-Aldrich(India) SML0240 Adefovir ≥98% (HPLC) 50MG ₹45876.3 2022-06-14 Buy

Properties

Melting point :>260°C
Boiling point :632.5±65.0 °C(Predicted)
Density :1.88
storage temp. :-20°C
solubility :0.1 M NaOH: ≥5mg/mL
pka :pKa1 2.0, pKa2 6.8(at 25℃)
form :powder
color :white to beige
InChIKey :SUPKOOSCJHTBAH-UHFFFAOYSA-N
CAS DataBase Reference :106941-25-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Adefovir (Trade name: Preveon, Hepsera) is a prescription drug used for the treatment of chronic infections of hepatitis B virus. It can be formulated as the pivoxil prodrug adefovir dipivoxil. However, it shows no effect against HIV-1. As a orally administrated acyclic nucleotide analog reverse transcriptase inhibitor, it blocking the reproduction of HBV through inhibiting the reverse transcriptase in the body. One of its advantages over another anti-HBV drug, lamivudine is that it is much harder for the virus to develop resistance to it.

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