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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >APHIDICOLIN

APHIDICOLIN

APHIDICOLIN Structure
  • ₹15290 - ₹109592.3
  • Product name: APHIDICOLIN
  • CAS: 38966-21-1
  • MF: C20H34O4
  • MW: 338.48
  • EINECS:609-602-3
  • MDL Number:MFCD00083214
  • Synonyms:(3-ALPHA,4-ALPHA,5-ALPHA,17-ALPHA)-3,17-DIHYDROXY-4-METHYL-9,15-CYCLO-C,18-DINOR-14,15-SECOANDROSTANE-4,17-DIMETHANOL;(+)-APHIDICOLIN;APHIDICOLIN;(+)-APHIDICOLIN, NIGROSPORA ORYZAE;,11a-beta,11b-beta))- ;9-dimethanol,tetradecahydro-3,9-11a-methano-11ah-cyclohepta(a)naphthalene-4 ;dihydroxy-4,11b-dimethyl-,(3r-(3-alpha,4-alpha,4a-alpha,6a-beta,8-beta,9-beta ;ici69653
7 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 10MG
  • 1ML
  • ManufacturerSigma-Aldrich(India)
  • Product numberA0781
  • Product descriptionAphidicolin from Nigrospora sphaerica ≥98% (HPLC), powder
  • Packaging10MG
  • Price₹109592.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number89458
  • Product descriptionAphidicolin analytical standard
  • Packaging5MG
  • Price₹84121.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA0781
  • Product descriptionAphidicolin from Nigrospora sphaerica ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹59115.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA0781
  • Product descriptionAphidicolin from Nigrospora sphaerica ≥98% (HPLC), powder
  • Packaging1MG
  • Price₹16064.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA4487
  • Product descriptionAphidicolin, Ready Made Solution from Nigrospora sphaerica
  • Packaging1ML
  • Price₹15534.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number178273
  • Product descriptionAphidicolin - CAS 38966-21-1 - Calbiochem Aphidicolin, CAS 38966-21-1, is a cell-permeable antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase.
  • Packaging1MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.04744
  • Product descriptionInSolution Aphidicolin - CAS 38966-21-1 - Calbiochem A 30 mM (1 mg/98 μL) sterile-filtered solution of Aphidicolin in DMSO.
  • Packaging1MG
  • Price₹15290
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A0781 Aphidicolin from Nigrospora sphaerica ≥98% (HPLC), powder 10MG ₹109592.3 2022-06-14 Buy
Sigma-Aldrich(India) 89458 Aphidicolin analytical standard 5MG ₹84121.08 2022-06-14 Buy
Sigma-Aldrich(India) A0781 Aphidicolin from Nigrospora sphaerica ≥98% (HPLC), powder 5MG ₹59115.33 2022-06-14 Buy
Sigma-Aldrich(India) A0781 Aphidicolin from Nigrospora sphaerica ≥98% (HPLC), powder 1MG ₹16064.3 2022-06-14 Buy
Sigma-Aldrich(India) A4487 Aphidicolin, Ready Made Solution from Nigrospora sphaerica 1ML ₹15534.4 2022-06-14 Buy
Sigma-Aldrich(India) 178273 Aphidicolin - CAS 38966-21-1 - Calbiochem Aphidicolin, CAS 38966-21-1, is a cell-permeable antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase. 1MG ₹15469.99 2022-06-14 Buy
Sigma-Aldrich(India) 5.04744 InSolution Aphidicolin - CAS 38966-21-1 - Calbiochem A 30 mM (1 mg/98 μL) sterile-filtered solution of Aphidicolin in DMSO. 1MG ₹15290 2022-06-14 Buy

Properties

Melting point :218-220°C
alpha :D27 +12° (c = 1 in methanol)
Boiling point :394.61°C (rough estimate)
Density :1.0057 (rough estimate)
vapor pressure :0.55 hPa ( 20 °C)
refractive index :1.4434 (estimate)
Flash point :87℃
storage temp. :2-8°C
solubility :ethanol: soluble1mg/mL (stable at least a week at 4°C.)
form :White solid
pka :14.24±0.70(Predicted)
color :colorless
optical activity :[α]27/D +12°, c = 1 in methanol(lit.)
Water Solubility :Soluble in DMSO or methanol. Insoluble in water. Store solutions at -20°
Merck :13,734
BRN :4689958
Stability :Stable for 2 years from date of purchase from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

(+)-Aphidicolin is a natural tetracyclic diterpene first isolated from the fungus C. aphidicola and shown to have antiviral activity against herpes simplex. In eukaryotic cells, it is a cell-permeable, reversible inhibitor of DNA replication, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels. Aphidicolin can be used, at 3 μM, to arrest cells in G1/S phase or to increase gene amplification frequency.

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