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Apoptolidin

Apoptolidin Structure
  • ₹79507.4
  • Product name: Apoptolidin
  • CAS: 194874-06-1
  • MF: C58H96O21
  • MW: 1129.38
  • EINECS:200-664-3
  • MDL Number:MFCD09752711
  • Synonyms:Apoptolidin;Apoptolidin A Ready Made Solution;FU 40A;L-glycero-α-D-galacto-2-Nonulopyranose, O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1→8)-3,5,7-trideoxy-1-C-[(2S,4S,5S,8E,10E,12R,13R,14E,16E,18E)-12-[(6-deoxy-4-O-methyl-α-L-glucopyranosyl)oxy]-5-hydroxy-4-methoxy-9,13,15,17,19-pentam...
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Brand

  • Sigma-Aldrich(India)

Package

  • 500μL
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0907
  • Product descriptionApoptolidin A Ready Made Solution 1?mg/mL in DMSO
  • Packaging500μL
  • Price₹79507.4
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0907 Apoptolidin A Ready Made Solution 1?mg/mL in DMSO 500μL ₹79507.4 2022-06-14 Buy

Properties

Melting point :128-130°
alpha :21D -5.2° (c = 1.0 in methanol)
Boiling point :1108.9±65.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
Flash point :87℃
storage temp. :-20°C
solubility :Soluble in DMSO, DMF, ethanol, or methanol.
pka :11.71±0.70(Predicted)
form :DMSO solution
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, ethanol or methanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 μM). Apoptolidin selectively kills transformed glial cells without significantly affecting untransformed cells. It also has antibiotic and antifungal actions.

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