BIX 01294

₹16200 - ₹78059.08
Product name: BIX 01294
CAS: 1392399-03-9
MF: C28H41Cl3N6O2
MW: 600.02314
EINECS:
MDL Number:MFCD16618384
Synonyms:BIX 01294 Trihydrochloride Hydrate;4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-, hydrochloride (1:3);2-(Hexahydro-4-Methyl-1H-1,4-Diazepin-1-yl)-6,7-Dimethoxy-[1-(Phenylmethyl)-4-Piperidynyl]-4-Quinazolinamine Trihydrochloride BIX01294 hydrochloride;BIX01294 hydrochloride;BIX01294 3hydrochloride;Trihydrochloride Hydrate;N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine;BIX 01204

Price3 Properties Safety Information Description

3 prices

Selected condition：

Brand

TCI Chemicals (India)
Sigma-Aldrich(India)

Package

5MG
25MG

ManufacturerTCI Chemicals (India)
Product numberB4211
Product descriptionBIX 01294 Trihydrochloride Hydrate
Packaging25MG
Price₹16200
Updated2022-05-26
Buy

ManufacturerSigma-Aldrich(India)
Product numberB9311
Product descriptionBIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder
Packaging5MG
Price₹19539.13
Updated2022-06-14
Buy

ManufacturerSigma-Aldrich(India)
Product numberB9311
Product descriptionBIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder
Packaging25MG
Price₹78059.08
Updated2022-06-14
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
TCI Chemicals (India)	B4211	BIX 01294 Trihydrochloride Hydrate	25MG	₹16200	2022-05-26	Buy
Sigma-Aldrich(India)	B9311	BIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder	5MG	₹19539.13	2022-06-14	Buy
Sigma-Aldrich(India)	B9311	BIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder	25MG	₹78059.08	2022-06-14	Buy

Properties

storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >20mg/mL
form :powder
color :white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BIX01294 hydrochloride inhibits G9a. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294 hydrochloride is a selective inhibitor of G9a HMTase (IC₅₀ = 1.7 μM). It less effectively inhibits the HMTase G9a-like protein (GLP; IC₅₀ = 38 μM) and has no effect on other known HMTases. BIX01294 hydrochloride has been used in combination with the calcium channel activator BayK8644 to facilitate the generation of induced pluripotent stem cells from somatic cells in vitro. BIX01294 hydrochloride is an inhibitor of HDAC.

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