CCG-1423
- ₹8000 - ₹52360.53
- Product name: CCG-1423
- CAS: 285986-88-1
- MF: C18H13ClF6N2O3
- MW: 454.75
- EINECS:
- MDL Number:MFCD01566719
- Synonyms:CCG-1423;N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide;N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide;N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423;N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide;Rho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem;CCG 1423;CCG-1423;CCG1423, >98%
5 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberC3449
- Product descriptionCCG-1423
- Packaging25MG
- Price₹8000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC3449
- Product descriptionCCG-1423
- Packaging100MG
- Price₹21800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0987
- Product descriptionCCG-1423 ≥98% (HPLC)
- Packaging25MG
- Price₹52360.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number555558
- Product descriptionRho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem The Rho/SRF Pathway Inhibitor, CCG-1423, also referenced under CAS 285986-88-1, controls the biological activity of Rho/SRF. This small molecule/inhib
- Packaging25MG
- Price₹16670.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0987
- Product descriptionCCG-1423 ≥98% (HPLC)
- Packaging5MG
- Price₹13000.83
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | C3449 | CCG-1423 | 25MG | ₹8000 | 2022-05-26 | Buy |
TCI Chemicals (India) | C3449 | CCG-1423 | 100MG | ₹21800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | SML0987 | CCG-1423 ≥98% (HPLC) | 25MG | ₹52360.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 555558 | Rho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem The Rho/SRF Pathway Inhibitor, CCG-1423, also referenced under CAS 285986-88-1, controls the biological activity of Rho/SRF. This small molecule/inhib | 25MG | ₹16670.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0987 | CCG-1423 ≥98% (HPLC) | 5MG | ₹13000.83 | 2022-06-14 | Buy |
Properties
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
CCG-1423 is a specific inhibitor of Rho pathway-mediated signalling and activation of serum response factor (SRF) transcription. The Rho family of small GTPases play a vital role in transduction of cell signalling events associated with several human cancers. It inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13 with an IC50 value of 1 μM. The site of inhibition in the pathway is not precisely defined but CCG-1423 appears to act on some aspect of the interaction of SRF with its transcriptional cofactor megakaryoblastic leukemia 1 (MKL1) at a point upstream of DNA binding. CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines at nanomolar to low micromolar concentrations.Related product price
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Suppliers and manufacturers
career henan chemical co
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ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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₹1.00 /1KG
N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide CAS:285986-88-1
N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide CAS:285986-88-1