Clofarabine
- ₹2600 - ₹45865.53
- Product name: Clofarabine
- CAS: 123318-82-1
- MF: C10H11ClFN5O3
- MW: 303.68
- EINECS:631-422-9
- MDL Number:MFCD00871077
- Synonyms:2-CHLORO-2'-ARABINOFLUORO-2'-DEOXYADENOSINE;5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;CLOFARABINE;CAFDA;2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-9h-purin-6-amin ;2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine ;Clofarabine2-CHLORO-9-(2'-DEOXY-2'-FLUORO-B-D-ARABINOFURANOSYL)ADENINE;5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 20MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberC2500
- Product descriptionClofarabine
- Packaging20MG
- Price₹2600
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC2500
- Product descriptionClofarabine
- Packaging100MG
- Price₹6400
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC7495
- Product descriptionClofarabine ≥98% (HPLC)
- Packaging5MG
- Price₹11387.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC7495
- Product descriptionClofarabine ≥98% (HPLC)
- Packaging25MG
- Price₹45865.53
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | C2500 | Clofarabine | 20MG | ₹2600 | 2022-05-26 | Buy |
TCI Chemicals (India) | C2500 | Clofarabine | 100MG | ₹6400 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | C7495 | Clofarabine ≥98% (HPLC) | 5MG | ₹11387.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C7495 | Clofarabine ≥98% (HPLC) | 25MG | ₹45865.53 | 2022-06-14 | Buy |
Properties
Melting point :228-2310C
Boiling point :550.0±60.0 °C(Predicted)
Density :1.4804 (estimate)
RTECS :UD7473000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :Powder
pka :12.56±0.70(Predicted)
color :white
λmax :263nm(EtOH)(lit.)
Merck :14,2372
InChIKey :INHHKRVRRUIAPA-KJHIFWANSA-N
CAS DataBase Reference :123318-82-1(CAS DataBase Reference)
Boiling point :550.0±60.0 °C(Predicted)
Density :1.4804 (estimate)
RTECS :UD7473000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :Powder
pka :12.56±0.70(Predicted)
color :white
λmax :263nm(EtOH)(lit.)
Merck :14,2372
InChIKey :INHHKRVRRUIAPA-KJHIFWANSA-N
CAS DataBase Reference :123318-82-1(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Clofarabine is a nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase-α (IC50s = 65 and 3.9 nM, respectively) and is cytotoxic to K562 myelogenous leukemia cells (IC50 = 5 nM). It induces apoptosis in primary chronic lymphocytic leukemia cells by directly altering mitochondrial transmembrane potential. Clofarabine demonstrates growth inhibition and cytotoxic activity in a variety of leukemias and solid tumors.Related product price
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