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ChemicalBook > Product Catalogue >Biochemical Engineering >Natural Products >Cryptotanshinone

Cryptotanshinone

Cryptotanshinone Structure
  • ₹4400 - ₹25720.2
  • Product name: Cryptotanshinone
  • CAS: 35825-57-1
  • MF: C19H20O3
  • MW: 296.36
  • EINECS:
  • MDL Number:MFCD07636810
  • Synonyms:98% BY HPLC;CRYPTOTANSHINONE >TANSHINONE, CRYPTO(P);(r)-1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione;TANSHINONE, CRYPTO;hexahydro-1,6,6-trimethyl-,(R)-;Phenanthro[1,2-b]furan-10,11-dione,1,2,6,7,8,9-;1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl[1,2-b]furan-10,11-dione
4 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 5MG
  • 25MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC5624
  • Product descriptionCryptotanshinone ≥98% (HPLC)
  • Packaging5MG
  • Price₹7620.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC5624
  • Product descriptionCryptotanshinone ≥98% (HPLC)
  • Packaging25MG
  • Price₹25720.2
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3363
  • Product descriptionCryptotanshinone
  • Packaging100MG
  • Price₹8000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3363
  • Product descriptionCryptotanshinone
  • Packaging25MG
  • Price₹4400
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C5624 Cryptotanshinone ≥98% (HPLC) 5MG ₹7620.8 2022-06-14 Buy
Sigma-Aldrich(India) C5624 Cryptotanshinone ≥98% (HPLC) 25MG ₹25720.2 2022-06-14 Buy
TCI Chemicals (India) C3363 Cryptotanshinone 100MG ₹8000 2022-05-26 Buy
TCI Chemicals (India) C3363 Cryptotanshinone 25MG ₹4400 2022-05-26 Buy

Properties

Melting point :192°C(lit.)
Boiling point :459.0±45.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
form :powder
color :orange-brown
optical activity :[α]/D -85.0±3.0°, c = 0.1 in chloroform
λmax :263nm(lit.)
BRN :5445400
InChIKey :IJSBKZLSTIFYIE-FPKDZHNTSA-N
LogP :4.130 (est)
CAS DataBase Reference :35825-57-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P501 Dispose of contents/container to..…

Description

Cryptotanshinone is a natural quinoid diterpene first isolated from Salvia miltiorrhiza roots, which are used in traditional Chinese medicine for a variety of conditions. Cryptotanshinone, at 10-20 μM, stimulates AMP-activated protein kinase in C2C12 myotubes and activates p38 MAPK in DU145 cells. It inhibits the protein tyrosine phosphatase SHP2 in vitro (IC50 = 22.5 μM) and, at 4-8 μM, blocks phosphorylation of STAT3 in MC-3 cells. Cryptotanshinone has a variety of anti-cancer actions, including inhibition of cell proliferation, induction of apoptosis, and reduction in angiogenesis. However, it is poorly absorbed and has low bioavailability in vivo.

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