Cyclosporin A
- ₹4400 - ₹48528.48
- Product name: Cyclosporin A
- CAS: 59865-13-3
- MF: C62H111N11O12
- MW: 1202.61
- EINECS:611-907-1
- MDL Number:MFCD00274558
- Synonyms:ol27-400 ;s7481f1 ;sandimmun ;Cyclospori;1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.;30-Ethyl-33-(1-hydroxy-2-methyl-hex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone;Cipol N;Neoplanta
12 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- 100MG
- 500MG
- 1ML
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberC2408
- Product descriptionCyclosporin A
- Packaging100MG
- Price₹4400
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC2408
- Product descriptionCyclosporin A
- Packaging1G
- Price₹9400
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1018
- Product descriptionCyclosporin A, Ready Made Solution 1?mg/mL in DMSO
- Packaging1ML
- Price₹13020.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1092
- Product descriptionCyclosporine Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging500MG
- Price₹15144.18
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number30024
- Product descriptionCyclosporin A 97.0-101.5% (on dried basis)
- Packaging25MG
- Price₹18218.48
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC3662
- Product descriptionCyclosporin A from Tolypocladium inflatum, ≥95% (HPLC), solid
- Packaging5MG
- Price₹20567.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC-093
- Product descriptionCyclosporin A solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹23487.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC1832
- Product descriptionCyclosporin A from Tolypocladium inflatum, BioReagent, for molecular biology, ≥95%
- Packaging5MG
- Price₹26954.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number32425
- Product descriptionCyclosporin A VETRANAL?, analytical standard
- Packaging100MG
- Price₹30591.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC3662
- Product descriptionCyclosporin A from Tolypocladium inflatum, ≥95% (HPLC), solid
- Packaging10MG
- Price₹34542.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number30024
- Product descriptionCyclosporin A 97.0-101.5% (on dried basis)
- Packaging100MG
- Price₹40030.85
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC1832
- Product descriptionCyclosporin A from Tolypocladium inflatum, BioReagent, for molecular biology, ≥95%
- Packaging10MG
- Price₹48528.48
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | C2408 | Cyclosporin A | 100MG | ₹4400 | 2022-05-26 | Buy |
TCI Chemicals (India) | C2408 | Cyclosporin A | 1G | ₹9400 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | SML1018 | Cyclosporin A, Ready Made Solution 1?mg/mL in DMSO | 1ML | ₹13020.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1092 | Cyclosporine Pharmaceutical Secondary Standard; Certified Reference Material | 500MG | ₹15144.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 30024 | Cyclosporin A 97.0-101.5% (on dried basis) | 25MG | ₹18218.48 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C3662 | Cyclosporin A from Tolypocladium inflatum, ≥95% (HPLC), solid | 5MG | ₹20567.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C-093 | Cyclosporin A solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹23487.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C1832 | Cyclosporin A from Tolypocladium inflatum, BioReagent, for molecular biology, ≥95% | 5MG | ₹26954.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 32425 | Cyclosporin A VETRANAL?, analytical standard | 100MG | ₹30591.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C3662 | Cyclosporin A from Tolypocladium inflatum, ≥95% (HPLC), solid | 10MG | ₹34542.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 30024 | Cyclosporin A 97.0-101.5% (on dried basis) | 100MG | ₹40030.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C1832 | Cyclosporin A from Tolypocladium inflatum, BioReagent, for molecular biology, ≥95% | 10MG | ₹48528.48 | 2022-06-14 | Buy |
Properties
Melting point :148-151°C
Boiling point :838.63°C (rough estimate)
alpha :D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Density :0.9913 (rough estimate)
refractive index :1.6500 (estimate)
Flash point :87℃
storage temp. :-20°C
solubility :ethanol: 30 mg/mL
form :solid
pka :13.32±0.70(Predicted)
color :white
Water Solubility :Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck :14,2752
BRN :3647785
Stability :Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference :59865-13-3(CAS DataBase Reference)
IARC :1 (Vol. 50, 100A) 2012
EPA Substance Registry System :Cyclosporin A (59865-13-3)
Boiling point :838.63°C (rough estimate)
alpha :D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Density :0.9913 (rough estimate)
refractive index :1.6500 (estimate)
Flash point :87℃
storage temp. :-20°C
solubility :ethanol: 30 mg/mL
form :solid
pka :13.32±0.70(Predicted)
color :white
Water Solubility :Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck :14,2752
BRN :3647785
Stability :Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference :59865-13-3(CAS DataBase Reference)
IARC :1 (Vol. 50, 100A) 2012
EPA Substance Registry System :Cyclosporin A (59865-13-3)
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM). It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT. Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.More related product prices
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