CYCLOTHIAZIDE
- ₹5000 - ₹27127.45
- Product name: CYCLOTHIAZIDE
- CAS: 2259-96-3
- MF: C14H16ClN3O4S2
- MW: 389.88
- EINECS:218-859-7
- MDL Number:MFCD00210192
- Synonyms:7-sulfonamide1,1-dioxide ;Anhydron;Aquirel;Doburil;Fluidil;Lilly 35483;lilly35,483 ;MDi 193
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberC3392
- Product descriptionCyclothiazide (mixture of isomers)
- Packaging25MG
- Price₹5000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC3392
- Product descriptionCyclothiazide (mixture of isomers)
- Packaging100MG
- Price₹12500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC9847
- Product descriptionCyclothiazide
- Packaging10MG
- Price₹13195.68
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC9847
- Product descriptionCyclothiazide
- Packaging25MG
- Price₹27127.45
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | C3392 | Cyclothiazide (mixture of isomers) | 25MG | ₹5000 | 2022-05-26 | Buy |
TCI Chemicals (India) | C3392 | Cyclothiazide (mixture of isomers) | 100MG | ₹12500 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | C9847 | Cyclothiazide | 10MG | ₹13195.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C9847 | Cyclothiazide | 25MG | ₹27127.45 | 2022-06-14 | Buy |
Properties
Melting point :234°
Density :1.3781 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 9 mg/ml)
pka :pKa 9.1(30% EtOH) (Uncertain)
form :White to off-white solid.
color :Off-white
λmax :273nm(lit.)
Merck :14,2754
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
EPA Substance Registry System :2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide (2259-96-3)
Density :1.3781 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 9 mg/ml)
pka :pKa 9.1(30% EtOH) (Uncertain)
form :White to off-white solid.
color :Off-white
λmax :273nm(lit.)
Merck :14,2754
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
EPA Substance Registry System :2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide (2259-96-3)
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Receptors for AMPA are ionotropic glutamate receptors with critical roles in neurological development and function. Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 μM). It blocks the rapid agonist-induced desensitization of AMPA receptors, resulting in enhanced excitatory activity. Cyclothiazide is also a negative modulator of GABAA receptors, reversibly inhibiting both evoked and spontaneous inhibitory postsynaptic currents (IC50 = 58 μM).Related product price
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₹3200-13996.73 - CYCLOTHIAZIDE
₹5000-27127.45 - Hydrochlorothiazide
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