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ChemicalBook > Product Catalogue >Natural Products >Anthraquinone >DAMNACANTHAL

DAMNACANTHAL

DAMNACANTHAL Structure
  • ₹17860
  • Product name: DAMNACANTHAL
  • CAS: 477-84-9
  • MF: C16H10O5
  • MW: 282.25
  • EINECS:
  • MDL Number:MFCD00674209
  • Synonyms:DAMNACANTHAL;DAMNACANTAL;1-Methoxy-2-formyl-3-hydroxy-9,10-anthraquinone;1-Methoxy-3-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carbaldehyde;3-HYDROXY-1-METHOXYANTHRAQUINONE-2-ALDEHYDE;1-Methoxy-3-hydroxy-9,10-dioxoanthracene-2-carbaldehyde;9,10-Dihydro-3-hydroxy-1-methoxy-9,10-dioxo-2-anthracenecarbaldehyde;3-hydroxy-1-methoxy-9,10-dioxo-anthracene-2-carbaldehyde
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product number251650
  • Product descriptionDamnacanthal - CAS 477-84-9 - Calbiochem A cell-permeable, potent, reversible, and selective inhibitor of p56lck tyrosine kinase.
  • Packaging1MG
  • Price₹17860
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 251650 Damnacanthal - CAS 477-84-9 - Calbiochem A cell-permeable, potent, reversible, and selective inhibitor of p56lck tyrosine kinase. 1MG ₹17860 2022-06-14 Buy

Properties

Melting point :218~219℃
Boiling point :531.9±50.0 °C(Predicted)
Density :1.461±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 7 mg/ml)
pka :5.26±0.20(Predicted)
form :Pale orange solid.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Damnacanthal (477-84-9) is a potent inhibitor of p56lck?tyrosine kinase activity (IC50?= 17 nM for inhibition of autophosphorylation). Displays 7- to 20-fold selectivity over p59fyn?and p60src?tyrosine kinases and > 40-fold to 100-fold selectivity over other kinases.1?Mobilizes intracellular Ca2+?in dermal fibroblasts.2?Inhibits LIM-kinase, impairing cell migration and invasion.3?A potent inhibitor of angiogenesis.4?Inhibits mast cell activation.5

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