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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Antihistamines >Desloratadine

Desloratadine

Desloratadine Structure
  • ₹1800 - ₹61778.28
  • Product name: Desloratadine
  • CAS: 100643-71-8
  • MF: C19H19ClN2
  • MW: 310.82
  • EINECS:638-878-8
  • MDL Number:MFCD00871949
  • Synonyms:AzoMyr;Neoclarityn;NSC 675447;Opulis;Desloratadine(Clarinex);5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro- 11-(4-piperidinylidene)-;Desloratadine for system suitability;Clarinex (TN)
5 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberD3787
  • Product descriptionDesloratadine
  • Packaging100MG
  • Price₹1800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD3787
  • Product descriptionDesloratadine
  • Packaging1G
  • Price₹8900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1680
  • Product descriptionDesloratidine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹11961.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1069
  • Product descriptionDesloratadine powder, ≥98% (HPLC)
  • Packaging10MG
  • Price₹16540.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1069
  • Product descriptionDesloratadine powder, ≥98% (HPLC)
  • Packaging50MG
  • Price₹61778.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D3787 Desloratadine 100MG ₹1800 2022-05-26 Buy
TCI Chemicals (India) D3787 Desloratadine 1G ₹8900 2022-05-26 Buy
Sigma-Aldrich(India) PHR1680 Desloratidine Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹11961.63 2022-06-14 Buy
Sigma-Aldrich(India) D1069 Desloratadine powder, ≥98% (HPLC) 10MG ₹16540.6 2022-06-14 Buy
Sigma-Aldrich(India) D1069 Desloratadine powder, ≥98% (HPLC) 50MG ₹61778.28 2022-06-14 Buy

Properties

Melting point :150-151°C
Boiling point :467.9±45.0 °C(Predicted)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :10.27±0.20(Predicted)
form :powder
color :White to Light orange to Yellow
Merck :14,2922
BCS Class :1
InChIKey :JAUOIFJMECXRGI-UHFFFAOYSA-N
CAS DataBase Reference :100643-71-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Desloratadine is a second generation of tricyclic antihistamine. It is a H1-receptor antagonist which has anti-inflammatory activity. Its affinity to the H1 receptor is higher than most other H1-receptor antagonists. Desloratadine works by blocking a certain natural substance (histamine) which is produced during an allergic reaction. Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Desloratadine is used to treat nasal and non-nasal symptoms (watery eyes, runny nose, itching eyes/nose, sneezing, and itching) of seasonal allergic rhinitis. It is also used to relieve chronic itching caused by hives.

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