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ChemicalBook > Product Catalogue >API >Drugs Influencing Immune Function >Immunosuppressive drugs >Diacerein

Diacerein

Diacerein Structure
  • ₹7605 - ₹25002
  • Product name: Diacerein
  • CAS: 13739-02-1
  • MF: C19H12O8
  • MW: 368.29
  • EINECS:237-310-2
  • MDL Number:MFCD00468030
  • Synonyms:1,8-DIACETOXY-3-CARBOXYANTHRAQUINONE;DIACEREIN;DIACERHEIN;DIACETYL RHEIN;9,10-dihydro-4,5-diacetoxy-9,10-2-anthracenecarboxylicacid ;9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicaciddiacetate ;9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicacidiacetate ;artrodar
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 10mg
  • 50MG
  • 100mg
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberD4061
  • Product descriptionDiacerein
  • Packaging1G
  • Price₹8900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4061
  • Product descriptionDiacerein
  • Packaging5G
  • Price₹19800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9302
  • Product descriptionDiacerein ≥95% (HPLC)
  • Packaging50MG
  • Price₹17471.55
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number D 1332
  • Product descriptionDiacerein, 95%
  • Packaging10mg
  • Price₹7605
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 1332
  • Product descriptionDiacerein, 95%
  • Packaging50mg
  • Price₹18189
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 1332
  • Product descriptionDiacerein, 95%
  • Packaging100mg
  • Price₹25002
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4061 Diacerein 1G ₹8900 2022-05-26 Buy
TCI Chemicals (India) D4061 Diacerein 5G ₹19800 2022-05-26 Buy
Sigma-Aldrich(India) D9302 Diacerein ≥95% (HPLC) 50MG ₹17471.55 2022-06-14 Buy
ottokemi D 1332 Diacerein, 95% 10mg ₹7605 2022-05-26 Buy
ottokemi D 1332 Diacerein, 95% 50mg ₹18189 2022-05-26 Buy
ottokemi D 1332 Diacerein, 95% 100mg ₹25002 2022-05-26 Buy

Properties

Melting point :217-2180C
Boiling point :631.5±55.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO (Sparingly), Methanol (Slightly)
pka :3.01±0.20(Predicted)
form :Solid
color :Light Yellow to Yellow
Water Solubility :240μg/L at 25℃
Merck :14,2960
InChIKey :TYNLGDBUJLVSMA-UHFFFAOYSA-N
LogP :3.126 (est)
CAS DataBase Reference :13739-02-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Diacerein is a diacetyl precursor of rhein, an anthraquinone found in plants. Rhein, at 10 μM, inhibits IL-1β signaling, suppressing signaling through NF-κB and AP-1, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13. Diacerein, presumably after conversion to rhein, down-regulates the expression of the IL-1β receptor on articular chondrocytes, enhances the expression of TGF-β, and increases collagen and aggrecan. It does not alter COX activity. It is mildly effective in ameliorating osteoarthritis.

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Siddhivinayakchemicals Micro Orgo Chem Global Pharma Gonane Pharma Medi Pharma Drug House Rivashaa Agrotech Biopharma Pvt. Ltd. ALS INDIA LIFE SCIENCES Believe Pharma Ralington Pharma Ami Lifesciences Pvt Ltd