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ChemicalBook > Product Catalogue >API >Respiratory Drugs >Asthma drugs >Doxofylline

Doxofylline

Doxofylline Structure
  • ₹7300 - ₹17200
  • Product name: Doxofylline
  • CAS: 69975-86-6
  • MF: C11H14N4O4
  • MW: 266.25
  • EINECS:274-239-6
  • MDL Number:MFCD00865218
  • Synonyms:DOXOFYLLINE;2-(7’-teofillinmetil)-1,3-diossolano ;Doxofyliine;7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethyl-purine-2,6-dione;DOXOFYLLINE [7-(1,3-DIOXOLAN-2-YLMETHYL)-3,7-DIHYDRO-1,3-DIMETHYL-1H-PURINE-2,6-DIONE];MAXIVENT;Ansirnar;Doxof3rlline
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • TCI Chemicals (India)

Package

  • 1G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberD4302
  • Product descriptionDoxofylline
  • Packaging1G
  • Price₹7300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4302
  • Product descriptionDoxofylline
  • Packaging25G
  • Price₹17200
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4302 Doxofylline 1G ₹7300 2022-05-26 Buy
TCI Chemicals (India) D4302 Doxofylline 25G ₹17200 2022-05-26 Buy

Properties

Melting point :144-146°C
Boiling point :409.46°C (rough estimate)
Density :1.2896 (rough estimate)
refractive index :1.6000 (estimate)
RTECS :XH5135000
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :0.42±0.70(Predicted)
color :White to Off-White
Water Solubility :Soluble
Merck :14,3438
InChI :InChI=1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3
InChIKey :HWXIGFIVGWUZAO-UHFFFAOYSA-N
SMILES :N1(CC2OCCO2)C2=C(N(C)C(=O)N(C)C2=O)N=C1
CAS DataBase Reference :69975-86-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Doxofylline is a methylxanthine bronchodilator that has been examined in clinical trials involving patients with either bronchial asthma or chronic obstructive pulmonary disease. Its mechanism of action is related to its ability to inhibit phosphodiesterase activity and, thus, increase cAMP. Compared to other xanthine derivatives, which have direct arrhythmogenic effects, doxofylline demonstrates decreased affinity towards adenosine A1 and A2 receptors, does not interfere with calcium influx into cells, and does not antagonize the action of calcium-channel blockers.

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HEMA PHARMACEUTICALS PVT LTD THE MOLECULEZ TRC FINE CHEMS SNECOFRi Pvt Ltd Jigs Chemical ltd Basic Pharma Life Science Pvt Ltd Aarti Industries Limited (AIL) Bajaj Healthcare Ltd Tivan Sciences Pvt Ltd Ralington Pharma