Exendin-4
- ₹27473.85 - ₹83092.7
- Product name: Exendin-4
- CAS: 141758-74-9
- MF: C184H282N50O60S
- MW: 4186.57188
- EINECS:686-356-3
- MDL Number:MFCD00240171
- Synonyms:EXENDIN-4;M.W. 4186.61 C184H282N50O60S;HIS-GLY-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;HIS-GLY-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2: HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2;Exenatide, AC 2993, Exendin A, ExendinA;Exendin-4 Exenatide;Exenatide (Exendin-4);Exenatide free base
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 500μG
- 0.1MG
- ManufacturerSigma-Aldrich(India)
- Product numberE7144
- Product descriptionExendin-4 ≥97%
- Packaging0.1MG
- Price₹27473.85
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE7144
- Product descriptionExendin-4 ≥97%
- Packaging500μG
- Price₹83092.7
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | E7144 | Exendin-4 ≥97% | 0.1MG | ₹27473.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E7144 | Exendin-4 ≥97% | 500μG | ₹83092.7 | 2022-06-14 | Buy |
Properties
RTECS :VT9545000
storage temp. :−20°C
solubility :≥145 mg/mL in DMSO; insoluble in EtOH; ≥52 mg/mL in H2O with gentle warming
form :White to off-white solid.
color :White to off-white
Water Solubility :Soluble in water (1 mg/ml)
InChIKey :HTQBXNHDCUEHJF-AAPNSGCPNA-N
storage temp. :−20°C
solubility :≥145 mg/mL in DMSO; insoluble in EtOH; ≥52 mg/mL in H2O with gentle warming
form :White to off-white solid.
color :White to off-white
Water Solubility :Soluble in water (1 mg/ml)
InChIKey :HTQBXNHDCUEHJF-AAPNSGCPNA-N
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
Exenatide is the first drug in a new class of anti-diabetics known as the incretin mimetics, and it is indicated as adjunctive therapy to improve glycemic control in patients with type 2 diabetes who are taking metformin, a sulfonylurea, or both, but have not achieved adequate glycemic control. Exenatide is a functional analog of the human incretin Glucagon-Like Peptide-1 (GLP-1). GLP-1 is naturally released from cells in the GI tract in response to food intake and acts on its receptor on b-cells to potentiate glucose-stimulated insulin secretion. Exenatide is a long-acting agonist at the GLP-1 receptor. It is a synthetic version of a 39-amino acid peptide found in the salivary secretions of the Gila monster lizard.also moderates peak serum glucagon levels during hyperglycemic periods following meals, but does not interfere with glucagon release in response to hypoglycemia. The dosing regimen for exenatide is 5 or 10 mg twice daily, administered as a subcutaneous injection within an hour before morning and evening meals. Following subcutaneous administration, peak plasma concentrations of exenatide are reached in 2.1 h, and the plasma pharmacokinetic profile is dose proportional. The most common adverse events reported with exenatide include nausea, vomiting, diarrhea, feeling jittery, dizziness, headache, and dyspepsia.More related product prices
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