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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >TOLBUTAMIDE

TOLBUTAMIDE

TOLBUTAMIDE Structure
  • ₹2600 - ₹32128.6
  • Product name: TOLBUTAMIDE
  • CAS: 64-77-7
  • MF: C12H18N2O3S
  • MW: 270.35
  • EINECS:200-594-3
  • MDL Number:MFCD00027169
  • Synonyms:Pramidex;Rastinon;Restinon;Sk-tolbutamide;tarasina ;tolbet ;Tolbusal;Tolbutamid
5 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 1G
  • 25G
  • 100G
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberT3690
  • Product descriptionTolbutamide
  • Packaging1G
  • Price₹2600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT0891
  • Product descriptionTolbutamide analytical standard
  • Packaging500G
  • Price₹32128.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT0891
  • Product descriptionTolbutamide analytical standard
  • Packaging100G
  • Price₹10121.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT0891
  • Product descriptionTolbutamide analytical standard
  • Packaging25G
  • Price₹5001.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number46968
  • Product descriptionTolbutamide VETRANAL?, analytical standard
  • Packaging250MG
  • Price₹4373.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T3690 Tolbutamide 1G ₹2600 2022-05-26 Buy
Sigma-Aldrich(India) T0891 Tolbutamide analytical standard 500G ₹32128.6 2022-06-14 Buy
Sigma-Aldrich(India) T0891 Tolbutamide analytical standard 100G ₹10121.38 2022-06-14 Buy
Sigma-Aldrich(India) T0891 Tolbutamide analytical standard 25G ₹5001.15 2022-06-14 Buy
Sigma-Aldrich(India) 46968 Tolbutamide VETRANAL?, analytical standard 250MG ₹4373.3 2022-06-14 Buy

Properties

Melting point :128-130°C
Density :1.2450
refractive index :1.6360 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in chloroform.
form :Solid
pka :pKa 5.32(H2O t = 37) (Uncertain)
color :White to Off-White
Water Solubility :0.14g/L(25 ºC)
Merck :14,9507
BRN :1984428
Specific Activity :50-60 mCi/mmol
Concentration :0.1 mCi/ml
Solvent :Ethanol
Stability :Stable. Combustible.
CAS DataBase Reference :64-77-7(CAS DataBase Reference)
EPA Substance Registry System :Tolbutamide (64-77-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.

Description

Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.

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