Ezetimibe
![]() |
- ₹13314.75 - ₹22743.33
- Product name: Ezetimibe
- CAS: 163222-33-1
- MF: C24H21F2NO3
- MW: 409.43
- EINECS:682-606-0
- MDL Number:MFCD00937872
- Synonyms:Ticagrelor and its interMediate;Ezetimibe 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;zetia/vytorin;SCH 60969;Ezetimibe, >=99%;(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azeti;1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;EZETIMIBE
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberSML1629
- Product descriptionEzetimibe ≥98% (HPLC)
- Packaging25MG
- Price₹13314.75
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1866
- Product descriptionEzetimibe Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹22743.33
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML1629 | Ezetimibe ≥98% (HPLC) | 25MG | ₹13314.75 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1866 | Ezetimibe Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹22743.33 | 2022-06-14 | Buy |
Properties
Melting point :164-166°C
alpha :D22 -33.9° (c = 3 in methanol)
Boiling point :654.9±55.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml)
pka :9.72±0.30(Predicted)
form :powder
color :White or off-white
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
InChIKey :OLNTVTPDXPETLC-XPWALMASSA-N
SMILES :N1(C2=CC=C(F)C=C2)[C@H](C2=CC=C(O)C=C2)[C@@H](CC[C@@H](C2=CC=C(F)C=C2)O)C1=O
CAS DataBase Reference :163222-33-1(CAS DataBase Reference)
EPA Substance Registry System :2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)- (163222-33-1)
alpha :D22 -33.9° (c = 3 in methanol)
Boiling point :654.9±55.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml)
pka :9.72±0.30(Predicted)
form :powder
color :White or off-white
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
InChIKey :OLNTVTPDXPETLC-XPWALMASSA-N
SMILES :N1(C2=CC=C(F)C=C2)[C@H](C2=CC=C(O)C=C2)[C@@H](CC[C@@H](C2=CC=C(F)C=C2)O)C1=O
CAS DataBase Reference :163222-33-1(CAS DataBase Reference)
EPA Substance Registry System :2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)- (163222-33-1)
Safety Information
Symbol(GHS): |
![]() |
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||
Hazard statements: |
|
||||||||||||||
Precautionary statements: |
|
Description
Ezetimibe is ananti-hyperlipidemic drug used for lowering the plasma cholesterol levels. It is indicated as an adjunctive therapy to diet for the reduction of high-level total-C, LDL-C, and ApoB in patients suffering primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors.Ezetimibe does not inhibit the cholesterol synthesis in the liver, or increase bile acid excretion.It takes effect throughacting at the brush border of the small intestine and inhibiting the absorption of cholesterol, further leading to a decrease in the delivery of intestinal cholesterol to the liver. This causes a reduction of hepatic cholesterol stores and an increase in clearance of blood cholesterol.More related product prices
Propyl gallate Boc-D-Glutamine CHLOROPHOSPHONAZO III Nicotinamide Acrylamide Isopropanol Propyl butyrate N,N-Dimethylformamide ent-EzetiMibe Etocrilene Exemestane Ezutromid EzetiMibe-d4 4-BENZYLIDENEAMINOPHENOL (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one 4-(4-Fluorobenzoyl)butyric acidRelated product price
- Propyl gallate
₹999-104645.28 - Boc-D-Glutamine
₹6500-49190 - CHLOROPHOSPHONAZO III
₹4180-73610