Nimesulide
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- ₹2200 - ₹56007
- Product name: Nimesulide
- CAS: 51803-78-2
- MF: C13H12N2O5S
- MW: 308.31
- EINECS:257-431-4
- MDL Number:MFCD00079470
- Synonyms:nimed ;4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE;CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD);4-Nitro-2-phenoxymethanesulfonamide;Nide;Nidol
10 prices
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Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
- ottokemi
Package
- 1G
- 1gm
- 5gm
- 5G
- 25gm
- 25G
- 100gm
- ManufacturerSigma-Aldrich(India)
- Product numberN1016
- Product descriptionNimesulide
- Packaging25G
- Price₹32648.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN1016
- Product descriptionNimesulide
- Packaging5G
- Price₹9959
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1336
- Product descriptionNimesulide Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹8919.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN1016
- Product descriptionNimesulide
- Packaging1G
- Price₹3085.13
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberN0984
- Product descriptionNimesulide
- Packaging5G
- Price₹4500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberN0984
- Product descriptionNimesulide
- Packaging1G
- Price₹2200
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number N 1630
- Product descriptionNimesulide, GR
- Packaging1gm
- Price₹2709
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number N 1630
- Product descriptionNimesulide, GR
- Packaging5gm
- Price₹9045
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number N 1630
- Product descriptionNimesulide, GR
- Packaging25gm
- Price₹29079
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number N 1630
- Product descriptionNimesulide, GR
- Packaging100gm
- Price₹56007
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | N1016 | Nimesulide | 25G | ₹32648.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N1016 | Nimesulide | 5G | ₹9959 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1336 | Nimesulide Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹8919.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N1016 | Nimesulide | 1G | ₹3085.13 | 2022-06-14 | Buy |
TCI Chemicals (India) | N0984 | Nimesulide | 5G | ₹4500 | 2022-05-26 | Buy |
TCI Chemicals (India) | N0984 | Nimesulide | 1G | ₹2200 | 2022-05-26 | Buy |
ottokemi | N 1630 | Nimesulide, GR | 1gm | ₹2709 | 2022-05-26 | Buy |
ottokemi | N 1630 | Nimesulide, GR | 5gm | ₹9045 | 2022-05-26 | Buy |
ottokemi | N 1630 | Nimesulide, GR | 25gm | ₹29079 | 2022-05-26 | Buy |
ottokemi | N 1630 | Nimesulide, GR | 100gm | ₹56007 | 2022-05-26 | Buy |
Properties
Melting point :140-146°C
Boiling point :442.0±55.0 °C(Predicted)
Density :1.451±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in acetone, slightly soluble in anhydrous ethanol.
form :Solid
pka :pKa 6.56± 0.03(H2O,t =25,I=0.02)(Approximate)
color :Light orange to Yellow to Green
biological source :synthetic (organic)
Water Solubility :Soluble in water (<50 µg/ml), 1:10 DMSO:PBS (pH 7.2) (<200 µg/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.
λmax :391nm(H2O)(lit.)
Merck :14,6548
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :HYWYRSMBCFDLJT-UHFFFAOYSA-N
CAS DataBase Reference :51803-78-2(CAS DataBase Reference)
EPA Substance Registry System :Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)- (51803-78-2)
Boiling point :442.0±55.0 °C(Predicted)
Density :1.451±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in acetone, slightly soluble in anhydrous ethanol.
form :Solid
pka :pKa 6.56± 0.03(H2O,t =25,I=0.02)(Approximate)
color :Light orange to Yellow to Green
biological source :synthetic (organic)
Water Solubility :Soluble in water (<50 µg/ml), 1:10 DMSO:PBS (pH 7.2) (<200 µg/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.
λmax :391nm(H2O)(lit.)
Merck :14,6548
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :HYWYRSMBCFDLJT-UHFFFAOYSA-N
CAS DataBase Reference :51803-78-2(CAS DataBase Reference)
EPA Substance Registry System :Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)- (51803-78-2)
Safety Information
Symbol(GHS): |
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Signal word: | Danger | ||||||||||||||
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Description
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. It is indicated for the treatment of acute pain, symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults. However, due to the risk of causing hepatotoxicity, it should not be taken long-term. It has also been withdrawn from the markets in many countries. It mechanism of action is through targeting on various key mediators in the inflammatory process such as COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine.More related product prices
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