P7C3
- ₹13931.78 - ₹56084.33
- Product name: P7C3
- CAS: 301353-96-8
- MF: C21H18Br2N2O
- MW: 474.19
- EINECS:
- MDL Number:MFCD00572918
- Synonyms:P7C3;1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(PHENYLAMINO)PROPAN-2-OL;3,6-Dibromo-a-[(phenylamino)methyl]-9H-carbazole-9-ethanol;P7C3, >=98%;6-Dibromo-α-[(phenylamino)methyl]-9H-carbazole-9-ethanol;P7C3; 301353-96-8;CS-1463;P7C3, >97%
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberD8446
- Product descriptionP7C3 ≥98% (HPLC)
- Packaging5MG
- Price₹13931.78
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD8446
- Product descriptionP7C3 ≥98% (HPLC)
- Packaging25MG
- Price₹56084.33
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D8446 | P7C3 ≥98% (HPLC) | 5MG | ₹13931.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D8446 | P7C3 ≥98% (HPLC) | 25MG | ₹56084.33 | 2022-06-14 | Buy |
Properties
Boiling point :656.4±55.0 °C(Predicted)
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble34mg/mL
pka :13.91±0.20(Predicted)
form :powder
color :white to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble34mg/mL
pka :13.91±0.20(Predicted)
form :powder
color :white to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
Safety Information
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Description
P7C3 is an orally bioavailable and brain penetrant aminopropyl carbazole that exhibits proneurogenic and neuroprotective activity by preventing apoptosis of newly postmitotic neurons in the subgranular zone of the hippocampal dentate gyrus. At doses of 5 mg/kg and above, it has been shown to promote the survival of neurons in various rodent models of neurodegeneration or nerve injury. While the precise mechanism of action through which these effects are exerted remains uncertain, P7C3 recently has been shown to bind nicotinamide phosphoribosyltransferase, the rate-limiting enzyme involved in the conversion of nicotinamide into NAD.Related product price
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