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ChemicalBook > Product Catalogue >Biochemical Engineering >Natural Products >Polydatin

Polydatin

Polydatin Structure
  • ₹1899 - ₹49005
  • Product name: Polydatin
  • CAS: 65914-17-2
  • MF: C20H22O8
  • MW: 390.38
  • EINECS:200-001-8
  • MDL Number:MFCD00210592
  • Synonyms:(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-(4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,;(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-(4-hydroxystyryl)phenoxy)-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol;3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside 97%;Piceid, Reservatrol-3-betta-Mono-D-glucoside, Resveratrol 3-O-betta-D-glucopyranoside;Polydatin SynonyMs Piceid, Reservatrol-3-betta-Mono-D-glucoside, Resveratrol 3-O-betta-D-glucopyranoside;β-D-Glucopyranoside, 3-hydroxy-5-[2-(4-hydroxyphenyl)ethenyl]phenyl;Polydatin 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside;-2-(3-Hydroxy-5-(4-hydroxystyryl)
7 prices
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Brand

  • Sigma-Aldrich
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 1G
  • 1gm
  • 5gm
  • 25gm
  • 25G
  • 100gm
  • ManufacturerSigma-Aldrich
  • Product number15721
  • Product descriptionPolydatin ≥95% (HPLC)
  • Packaging25G
  • Price₹17038.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number15721
  • Product descriptionPolydatin ≥95% (HPLC)
  • Packaging25G
  • Price₹17038.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number572691
  • Product description3,4′-5-Trihydroxystilbene-3-β-D-glucopyranoside 97%
  • Packaging1G
  • Price₹19539.13
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number P 1973
  • Product descriptionPolydatin, ≥95% (HPLC) 95%
  • Packaging1gm
  • Price₹1899
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1973
  • Product descriptionPolydatin, ≥95% (HPLC) 95%
  • Packaging5gm
  • Price₹7605
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1973
  • Product descriptionPolydatin, ≥95% (HPLC) 95%
  • Packaging25gm
  • Price₹15003
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1973
  • Product descriptionPolydatin, ≥95% (HPLC) 95%
  • Packaging100gm
  • Price₹49005
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 15721 Polydatin ≥95% (HPLC) 25G ₹17038.55 2022-06-14 Buy
Sigma-Aldrich(India) 15721 Polydatin ≥95% (HPLC) 25G ₹17038.55 2022-06-14 Buy
Sigma-Aldrich(India) 572691 3,4′-5-Trihydroxystilbene-3-β-D-glucopyranoside 97% 1G ₹19539.13 2022-06-14 Buy
ottokemi P 1973 Polydatin, ≥95% (HPLC) 95% 1gm ₹1899 2022-05-26 Buy
ottokemi P 1973 Polydatin, ≥95% (HPLC) 95% 5gm ₹7605 2022-05-26 Buy
ottokemi P 1973 Polydatin, ≥95% (HPLC) 95% 25gm ₹15003 2022-05-26 Buy
ottokemi P 1973 Polydatin, ≥95% (HPLC) 95% 100gm ₹49005 2022-05-26 Buy

Properties

Melting point :223-226 °C(lit.)
alpha :-55 º (c=1,acetone)
Boiling point :707.7±60.0 °C(Predicted)
Density :1.521±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO (Slightly), Ethanol (Sparingly), Methanol (Slightly), Water (Slightly)
pka :9.31±0.10(Predicted)
form :White to off-white solid.
color :White to off-white solid.
optical activity :[α]20/D 55°, c = 1 in acetone
BRN :54837
LogP :0.412 (est)
CAS DataBase Reference :65914-17-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Polydatin (PD) is a major chemical component of Polygonum cuspidatum and it could also be found in a variety of other sources. PD is a polyphenol belonging to the chemical family of stilbenoids. Previous studies have shown that PD exhibits many pharmacological activities, including cardioprotective, neuroprotective, and antioxidative activities. With vascular dementia (VaD) rat models, PD markedly attenuated cognitive deficits. Biochemical analysis revealed that PD decreased the production of malondialdehyde (MDA) and significantly increased superoxide dismutase and catalase activities. Additionally, PD effectively alleviated the injuries of cultured neurons induced by oxygen–glucose deprivation. The therapeutic potential of PD for VaD seems related to its antioxidative activity and the direct protection of neurons. Furthermore, PD could also effectively inhibit the polymerization of amyloid-β peptides, which is a major mark in the progression of pathogenesis in Alzheimer’s disease (AD). These results suggest that PD is a promising drug candidate or nutraceutical for the treatment of VaD and AD.

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