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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Lipid regulating drugs >Probucol

Probucol

Probucol Structure
  • ₹5900 - ₹74649.2
  • Product name: Probucol
  • CAS: 23288-49-5
  • MF: C31H48O2S2
  • MW: 516.84
  • EINECS:245-560-9
  • MDL Number:MFCD00079281
  • Synonyms:PROBUCOL;4,4’-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl)-pheno ;biphenabid ;bisbid ;bisphenabid ;Probucol (200 mg);Probucol-[13C3];Bis(3,5-di-tert-butyl-4-hydroxyphenyl) Mercaptole Acetone
6 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 500MG
  • 1G
  • 5G
  • 25G
  • 50G
  • ManufacturerTCI Chemicals (India)
  • Product numberP2002
  • Product descriptionProbucol
  • Packaging5G
  • Price₹5900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP2002
  • Product descriptionProbucol
  • Packaging25G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP9672
  • Product descriptionProbucol analytical standard
  • Packaging50G
  • Price₹74649.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3113
  • Product descriptionProbucol Related Compound A pharmaceutical secondary standard, certified reference material
  • Packaging50MG
  • Price₹61605.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3112
  • Product descriptionProbucol pharmaceutical secondary standard, certified reference material
  • Packaging500MG
  • Price₹15598.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP9672
  • Product descriptionProbucol analytical standard
  • Packaging1G
  • Price₹15544.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P2002 Probucol 5G ₹5900 2022-05-26 Buy
TCI Chemicals (India) P2002 Probucol 25G ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) P9672 Probucol analytical standard 50G ₹74649.2 2022-06-14 Buy
Sigma-Aldrich(India) PHR3113 Probucol Related Compound A pharmaceutical secondary standard, certified reference material 50MG ₹61605.08 2022-06-14 Buy
Sigma-Aldrich(India) PHR3112 Probucol pharmaceutical secondary standard, certified reference material 500MG ₹15598.83 2022-06-14 Buy
Sigma-Aldrich(India) P9672 Probucol analytical standard 1G ₹15544.7 2022-06-14 Buy

Properties

Melting point :126-128°C
Boiling point :571.58°C (rough estimate)
Density :1.0008 (rough estimate)
refractive index :1.5341 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :10.27±0.70(Predicted)
color :White to Off-White
Merck :14,7755
InChIKey :FYPMFJGVHOHGLL-UHFFFAOYSA-N
CAS DataBase Reference :23288-49-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Probucol is a kind of bis-phenol antioxidant with anti-hyperlipidemic activity. It had been initially developed for the treatment of coronary artery disease. However, its clinical trials were stopped after people found that it could lower the HDL and LDL cholesterol in patients of a history of heart disease. Probucol exerts its effect through accelerating the fractional rate of low-density (LDL) catabolism which is in the final pathway of cholesterol elimination inside the body. It may also inhibit the early stage of cholesterol biosynthesis and dietary cholesterol absorption.

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