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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antipsychotics >Quetiapine fumarate

Quetiapine fumarate

Quetiapine fumarate Structure
  • ₹9428.58 - ₹38829.28
  • Product name: Quetiapine fumarate
  • CAS: 111974-72-2
  • MF: C25H29N3O6S
  • MW: 499.58
  • EINECS:1308068-626-2
  • MDL Number:MFCD03423782
  • Synonyms:QUETIAPINE HEMIFUMERATE;Quetiapine fuMarate USP;2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol,(2E)-2-butenedioate (2:1);Quetiapine fumarate solution;Quetiapine for system suitability;QuetiapineFamarate;Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (2:1);2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate
6 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 1ML
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberQ0092
  • Product descriptionQuetiapine Hemifumarate
  • Packaging5G
  • Price₹9600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberQ0092
  • Product descriptionQuetiapine Hemifumarate
  • Packaging25G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberQ3638
  • Product descriptionQuetiapine hemifumarate salt ≥98% (HPLC)
  • Packaging10MG
  • Price₹9428.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberQ-001
  • Product descriptionQuetiapine fumarate solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹10041.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1856
  • Product descriptionQuetiapine Fumarate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹18759.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberQ3638
  • Product descriptionQuetiapine hemifumarate salt ≥98% (HPLC)
  • Packaging50MG
  • Price₹38829.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) Q0092 Quetiapine Hemifumarate 5G ₹9600 2022-05-26 Buy
TCI Chemicals (India) Q0092 Quetiapine Hemifumarate 25G ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) Q3638 Quetiapine hemifumarate salt ≥98% (HPLC) 10MG ₹9428.58 2022-06-14 Buy
Sigma-Aldrich(India) Q-001 Quetiapine fumarate solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹10041.5 2022-06-14 Buy
Sigma-Aldrich(India) PHR1856 Quetiapine Fumarate Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹18759.73 2022-06-14 Buy
Sigma-Aldrich(India) Q3638 Quetiapine hemifumarate salt ≥98% (HPLC) 50MG ₹38829.28 2022-06-14 Buy

Properties

Melting point :174-176°C
Flash point :9℃
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :powder
color :white to off-white
Merck :14,8039
BCS Class :2
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :111974-72-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Quetiapine is an atypical, second generation antipsychotic compound. It has effects at multiple receptors, antagonizing dopamine D1, D2, and D3 receptors (Kis = 994, 379, and 340 nM, respectively), serotonin 5-HT1A, 5-HT2A, and 5-HT7 receptors (Kis = 394, 118, and 307 nM, respectively), and α1A, α1B, and α2C adrenergic receptors (Kis = 22, 15, and 29 nM, respectively). Quetiapine also potently antagonizes the histamine H1 receptor (Ki = 11 nM).

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