Rosuvastatin calcium
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- ₹10300 - ₹43613.93
- Product name: Rosuvastatin calcium
- CAS: 147098-20-2
- MF: C22H30CaFN3O6S
- MW: 523.63
- EINECS:627-028-1
- MDL Number:MFCD04112702
- Synonyms:(+)-bis[7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3R,5S-dihydroxy-6(E)-heptenoic acid]calcium salt;calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethan-3-ylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate;ZD4522;(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Hep;Rosuvastatin (as Ca salt);ROSUVASTATIN, CALCIUM SALT;ROSUVASTATIN CALCIUM;Calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-y
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 200MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberR0180
- Product descriptionRosuvastatin Calcium
- Packaging200MG
- Price₹10300
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1264
- Product descriptionRosuvastatin calcium ≥98% (HPLC)
- Packaging10MG
- Price₹10716.75
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1928
- Product descriptionRosuvastatin Calcium Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹23739.23
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1264
- Product descriptionRosuvastatin calcium ≥98% (HPLC)
- Packaging50MG
- Price₹43613.93
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | R0180 | Rosuvastatin Calcium | 200MG | ₹10300 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | SML1264 | Rosuvastatin calcium ≥98% (HPLC) | 10MG | ₹10716.75 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1928 | Rosuvastatin Calcium Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹23739.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML1264 | Rosuvastatin calcium ≥98% (HPLC) | 50MG | ₹43613.93 | 2022-06-14 | Buy |
Properties
Melting point :122°C
alpha :D24 +14.8° (c = 1.012 in 50% methanol)
storage temp. :2-8°C
solubility :DMSO : 25 mg/mL (49.94 mM; Need ultrasonic)H2O : 1 mg/mL (2.00 mM; Need ultrasonic)
form :powder
color :white to beige
optical activity :[α]/D +12 to +18°, c = 1 in methanol: water (1:1)
λmax :243nm(Phosphate buffer sol.)(lit.)
Merck :14,8270
InChIKey :JSVIQRTVYKCCOM-LMRKSJJTNA-N
SMILES :C(/C1=C(N=C(N(C)S(=O)(=O)C)N=C1C1C=CC(F)=CC=1)C(C)C)=C\[C@@H](O)C[C@@H](O)CC(=O)O.[Ca] |&1:24,27,r|
CAS DataBase Reference :147098-20-2(CAS DataBase Reference)
alpha :D24 +14.8° (c = 1.012 in 50% methanol)
storage temp. :2-8°C
solubility :DMSO : 25 mg/mL (49.94 mM; Need ultrasonic)H2O : 1 mg/mL (2.00 mM; Need ultrasonic)
form :powder
color :white to beige
optical activity :[α]/D +12 to +18°, c = 1 in methanol: water (1:1)
λmax :243nm(Phosphate buffer sol.)(lit.)
Merck :14,8270
InChIKey :JSVIQRTVYKCCOM-LMRKSJJTNA-N
SMILES :C(/C1=C(N=C(N(C)S(=O)(=O)C)N=C1C1C=CC(F)=CC=1)C(C)C)=C\[C@@H](O)C[C@@H](O)CC(=O)O.[Ca] |&1:24,27,r|
CAS DataBase Reference :147098-20-2(CAS DataBase Reference)
Safety Information
Symbol(GHS): |
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Description
Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the “statin” class of cholesterol-lowering drugs. Rosuvastatin is an HMG-CoA reductase inhibitor (IC50 = 5 nM). It is a fully-synthetic inhibitor that is designed to maximize the points of contact with, and inhibition of, HMG-CoA reductase. Rosuvastatin reduces low-density lipoprotein and C-reactive protein and increases high-density lipoprotein in clinical trials.More related product prices
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