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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Trifluridine

Trifluridine

Trifluridine Structure
  • ₹2380 - ₹169616.93
  • Product name: Trifluridine
  • CAS: 70-00-8
  • MF: C10H11F3N2O5
  • MW: 296.2
  • EINECS:200-722-8
  • MDL Number:MFCD00006534
  • Synonyms:5-TRIFLUORO THYMIDINE;2''-DEOXY-5-(TRIFLUOROMETHYL)URIDINE (TRIFLUOROTHYMIDINE);2’-deoxy-5-(trifluoromethyl)-uridin ;5-(trifluoromethyl)deoxyuridine ;5-trifluoro-2’-deoxythymidine ;alpha,alpha,alpha-trifluoro-thymidin ;f3dthd ;5-TRIFLUOROTHYMIDINE extrapure (Trifluridine)
7 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 25mg
  • 100MG
  • 200MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberT2511
  • Product descriptionTrifluorothymidine
  • Packaging100MG
  • Price₹9200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2511
  • Product descriptionTrifluorothymidine
  • Packaging1G
  • Price₹37500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2255
  • Product descriptionTrifluorothymidine ≥99% (HPLC)
  • Packaging100MG
  • Price₹26856.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3150
  • Product descriptionTrifluridine pharmaceutical secondary standard, certified reference material
  • Packaging200MG
  • Price₹27040.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2255
  • Product descriptionTrifluorothymidine ≥99% (HPLC)
  • Packaging1G
  • Price₹169616.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number79009
  • Product description5-Trifluorothymidine extrapure, 99%
  • Packaging25mg
  • Price₹2380
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number79009
  • Product description5-Trifluorothymidine extrapure, 99%
  • Packaging100mg
  • Price₹8220
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T2511 Trifluorothymidine 100MG ₹9200 2022-05-26 Buy
TCI Chemicals (India) T2511 Trifluorothymidine 1G ₹37500 2022-05-26 Buy
Sigma-Aldrich(India) T2255 Trifluorothymidine ≥99% (HPLC) 100MG ₹26856.83 2022-06-14 Buy
Sigma-Aldrich(India) PHR3150 Trifluridine pharmaceutical secondary standard, certified reference material 200MG ₹27040.85 2022-06-14 Buy
Sigma-Aldrich(India) T2255 Trifluorothymidine ≥99% (HPLC) 1G ₹169616.93 2022-06-14 Buy
SRL 79009 5-Trifluorothymidine extrapure, 99% 25mg ₹2380 2022-05-26 Buy
SRL 79009 5-Trifluorothymidine extrapure, 99% 100mg ₹8220 2022-05-26 Buy

Properties

Melting point :190-193 °C (lit.)
Density :1.4365 (estimate)
refractive index :50 ° (C=1, H2O)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)
form :solid
pka :pKa 7.85 (Uncertain)
color :Off-white
Merck :14,9687
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
CAS DataBase Reference :70-00-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Trifluridine (trifluorothymidine, TFT), a fluorinated pyrimidine nucleoside, is an anti-herpesvirus agent and an antitumor antimetabolite agent. It is an analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity. After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes. Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.

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