Alpha-D-Lactose monohydrate
- CAS No.
- 5989-81-1
- Chemical Name:
- Alpha-D-Lactose monohydrate
- Synonyms
- LACTOSE MONOHYDRATE;α-Lactose;MILK SUGAR;ALPHA-LACTOSE MONOHYDRATE;ALPHA-D-LACTOSE;α-D-Lactose monohydrate;A-LACTOSE;Pharmatose 150M;ALPHA-LACTOSE MONOHY;A-LACTOSE MONOHYDRATE
- CBNumber:
- CB0177832
- Molecular Formula:
- C12H24O12
- Molecular Weight:
- 360.31
- MOL File:
- 5989-81-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/17 21:30:02
| Melting point | 219 °C |
|---|---|
| Boiling point | 412.35°C (rough estimate) |
| alpha | [α]D20+52.2～+52.8° |
| Density | 1,53 g/cm3 |
| RTECS | OD9625000 |
| refractive index | 1.6480 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: soluble1M, clear, colorless |
| form | Solid |
| color | White to Off-White |
| PH | pH (50g/l, 25℃) : 4.0～6.0 |
| Water Solubility | Soluble in water. |
| Stability | Hygroscopic |
| InChIKey | WSVLPVUVIUVCRA-KPKNDVKVSA-N |
| CAS DataBase Reference | 5989-81-1(CAS DataBase Reference) |
| EPA Substance Registry System | .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1) (5989-81-1) |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xi | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Risk Statements | 40-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 17021100 | |||||||||
| NFPA 704 |
|
Alpha-D-Lactose monohydrate price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | L8783 | α-Lactose monohydrate BioXtra, ≥99% total lactose basis (GC) | 5989-81-1 | 10MG | ₹2703 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L8783 | α-Lactose monohydrate BioXtra, ≥99% total lactose basis (GC) | 5989-81-1 | 1KG | ₹8096.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L8783 | α-Lactose monohydrate BioXtra, ≥99% total lactose basis (GC) | 5989-81-1 | 5KG | ₹32181 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L3625 | α-Lactose monohydrate ≥99% total lactose basis (GC) | 5989-81-1 | 1KG | ₹6298.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L3625 | α-Lactose monohydrate ≥99% total lactose basis (GC) | 5989-81-1 | 5KG | ₹13731.75 | 2022-06-14 | Buy |
Alpha-D-Lactose monohydrate Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.
Definition
A sugar that occurs in many plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme invertase. Since this mixture has a different optical rotation (levorotatory) than the original sucrose, the mixture is called invert sugar.
Production Methods
A suspension of a-lactose monohydrate crystals in a lactose solution is atomized and dried in a spray drier. Approximately 10–20% of the total amount of lactose is in solution and the remaining 80–90% is present in the crystalline form. The spray-drying process predominantly produces spherical particles. The compactibility of the material and its flow characteristics are a function of the primary particle size of the lactose monohydrate and the amount of amorphous lactose.
Pharmaceutical Applications
Spray-dried lactose is widely used as a binder, filler-binder, and flow aid in direct compression tableting.
Safety
Lactose is widely used in pharmaceutical formulations as a diluent
in oral capsule and tablet formulations. It may also be used in
intravenous injections.
Adverse reactions to lactose are largely due to lactose intolerance,
which occurs in individuals with a deficiency of the enzyme
lactase.
storage
Spray-dried lactose should be stored in a well-closed container in a cool, dry place.
Incompatibilities
Lactose is a reducing sugar. The amorphous lactose, which is the most reactive form of lactose present in spray-dried lactose, will interact more readily than conventional crystalline grades. Typical reactions include the Maillard reaction with either primary or secondary amines.
Alpha-D-Lactose monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Biokemix | +91 (40) 6662-6366 | New Delhi, India | 487 | 50 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Bavaria Pharma | 08048372623Ext 470 | Vadodara, India | 28 | 58 | Inquiry |
| Organic Chemicals | 08048372709Ext 384 | Pune, India | 75 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20293 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Supplier | Advantage |
|---|---|
| Scientific OEM | 38 |
| ALPHA CHEMIKA | 43 |
| Biokemix | 50 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Bavaria Pharma | 58 |
| Organic Chemicals | 58 |
| Henan Fengda Chemical Co., Ltd | 58 |
| Capot Chemical Co.,Ltd. | 60 |
5989-81-1(Alpha-D-Lactose monohydrate)Related Search:
1of4
chevron_right